Metakrón penismetastasis rectum-adenocarcinomából

Zsófia Küronya, István Bodrogi, József Lövey, Vanda Plótár, Sándor Manninger, Zsuzsanna Pápai

Research output: Short survey

5 Citations (Scopus)

Abstract

Despite of its rich vascularization and extensive circulatory communication with neighboring organs, penile metastases are rare. Even more infrequent is a penile metastasis of rectum tumors. Since the first report of rectal carcinoma with metastasis to the penis (Ehbert 1870), approximately 50 cases have been reported, most of them from the USA, the remaining from Western Europe, the Middle East and Japan. The first Hungarian case is reported now of penile metastasis of a rectal carcinoma. The case of a 65-year-old man is presented: isolated penile metastasis discovered 4.5 years after the primary rectal cancer resection. IHC tissue diagnosis and detailed clinical investigations confirmed metastatic rectal adenocarcinoma. As our patient refused penectomy and KRAS mutation was proven, FOLFIRI chemotherapy was initiated without cetuximab. This was followed by chemoradiotherapy that resulted only in transient regression. Currently the patient receives the FOLFOX regimen. At present the patient is in good performance status,without pain. The size and the number of penile metastases have not shown significant changes. According to the literature the average survival of patients with penile metastases treated with radiochemotherapy is 8 months. New chemotherapeutic modalities may improve the survival.

Translated title of the contributionMetachronous metastasis to the penis from carcinoma of the rectum: Case report
Original languageHungarian
Pages (from-to)263-266
Number of pages4
JournalMagyar onkologia
Volume53
Issue number3
DOIs
Publication statusPublished - szept. 1 2009

Keywords

  • Chemoradiotherapy
  • FOLFIRI
  • FOLFOX
  • KRAS
  • Metastasis
  • Penis
  • Rectal adenocarcinoma

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Küronya, Z., Bodrogi, I., Lövey, J., Plótár, V., Manninger, S., & Pápai, Z. (2009). Metakrón penismetastasis rectum-adenocarcinomából. Magyar onkologia, 53(3), 263-266. https://doi.org/10.1556/MOnkol.53.2009.3.5