Keratitis caused by the recently described new species Aspergillus brasiliensis: Two case reports

Palanisamy Manikandan, János Varga, Sándor Kocsubé, Rajaraman Revathi, Raghavan Anita, Ilona Dóczi, Tibor Mihály Németh, Venkatapathy Narendran, Csaba Vágvölgyi, Madhavan Bhaskar, Chockaiya Manoharan, Robert A. Samson, László Kredics

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Introduction. Human infections caused by Aspergillus brasiliensis have not yet been reported. We describe the first two known cases of fungal keratitis caused by Aspergillus brasiliensis. Case presentations. A 49-year-old Indian Tamil woman agricultural worker came with pain and defective vision in the right eye for one month. Meanwhile, a 35-year-old Indian Tamil woman presented with a history of a corneal ulcer involving the left eye for 15 days. The fungal strains isolated from these two cases were originally suspected to belong to Aspergillus section Nigri based on macro- and micromorphological characteristics. Molecular identification revealed that both isolates represent A. brasiliensis. Conclusion. The two A. brasiliensis strains examined in this study were part of six keratitis isolates from Aspergillus section Nigri, suggesting that this recently described species may be responsible for a significant proportion of corneal infections caused by black Aspergilli. The presented cases also indicate that significant differences may occur between the severities of keratitis caused by individual isolates of A. brasiliensis.

Original languageEnglish
Article number68
JournalJournal of Medical Case Reports
Publication statusPublished - máj. 28 2010


ASJC Scopus subject areas

  • Medicine(all)

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