Isolation and properties of two biologically active fragments from limited tryptic hydrolysis of bovine and ovine pituitary growth hormones

László Gráf, Choh Hao Li

Research output: Article

27 Citations (Scopus)

Abstract

Limited tryptic hydrolysis of bovine and ovine pituitary growth hormones has been investigated. From both hormones, a peptide fragment consisting of 38 amino acid residues corresponding to residue positions 96-133 in the structure has been isolated and characterized. It possesses measurable activity in the tibia test for growth-promoting activity. Another peptide fragment derived from the COOH-terminal portion (residues 151-191) of bovine growth hormone has also been isolated and characterized. It too gives measurable response in the tibia test.

Original languageEnglish
Pages (from-to)5408-5415
Number of pages8
JournalBiochemistry
Volume13
Issue number26
DOIs
Publication statusPublished - dec. 1 1974

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ASJC Scopus subject areas

  • Biochemistry

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