Is retinopathy in pancreatitis caused by leukocyte emboli?

G. Holló, E. Popik

Research output: Article

9 Citations (Scopus)

Abstract

The theory of granulocyte embolization in the retinal arterioles in acute pancreatitis cannot account for several aspects of the ophthalmic complication. Therefore we studied retinal circulation by fluorescein angiography, light and transmission electron microscopy following the first six hours of acute experimental necrotizing pancreatitis. The studied period was characterized by high serum lipase and amylase concentrations, hypocalcemia, necrosis of the pancreatic tissue and preceded the development of hypovolemic shock. Ophthalmoscopy and fluorescein angiography revealed no pathologic alterations and no granulocyte aggregation was found. Our results suggest that granulocyte aggregation induced by pancreatic enzymes is not the reason for the ophthalmic circulatory disturbances in acute pancreatitis.

Original languageEnglish
Pages (from-to)820-823
Number of pages4
JournalActa Ophthalmologica
Volume70
Issue number6
Publication statusPublished - 1992

Fingerprint

Embolism
Granulocytes
Pancreatitis
Leukocytes
Fluorescein Angiography
Acute Necrotizing Pancreatitis
Ophthalmoscopy
Hypocalcemia
Arterioles
Amylases
Lipase
Transmission Electron Microscopy
Shock
Necrosis
Light
Enzymes
Serum

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Is retinopathy in pancreatitis caused by leukocyte emboli? / Holló, G.; Popik, E.

In: Acta Ophthalmologica, Vol. 70, No. 6, 1992, p. 820-823.

Research output: Article

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