Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults

Gergely Darnai, Szilvia Anett Nagy, Réka Horváth, Péter Ács, Gábor Perlaki, Gergely Orsi, N. Kovács, Anna Altbäcker, Enik Plózer, Dalma Tényi, Rita Weintraut, Attila Schwarcz, Flóra John, Eszter Varga, T. Bereczkei, Z. Clemens, S. Komoly, J. Janszky

Research output: Article

1 Citation (Scopus)

Abstract

Abnormally high deposition of iron can contribute to neurodegenerative disorders with cognitive impairment. Since previous studies investigating cognition-brain iron accumulation relationships focused on elderly people, our aim was to explore the association between iron concentration in subcortical nuclei and two types of memory performances in a healthy young population. Gender difference was found only in the globus pallidus. Our results showed that iron load characterized by R2∗ value on the MRI in the caudate and putamen was related to visual memory, while verbal memory was unrelated to iron concentration.

Original languageEnglish
Pages (from-to)675-681
Number of pages7
JournalJournal of Alzheimer's Disease
Volume59
Issue number2
DOIs
Publication statusPublished - jan. 1 2017

ASJC Scopus subject areas

  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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    Darnai, G., Nagy, S. A., Horváth, R., Ács, P., Perlaki, G., Orsi, G., Kovács, N., Altbäcker, A., Plózer, E., Tényi, D., Weintraut, R., Schwarcz, A., John, F., Varga, E., Bereczkei, T., Clemens, Z., Komoly, S., & Janszky, J. (2017). Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults. Journal of Alzheimer's Disease, 59(2), 675-681. https://doi.org/10.3233/JAD-170118