The effect of fibrinogen degradation products (FDP) of the 'late' type (D and E fragments) on the ethanol gelation test has been examined at different fibrinogen and fibrin monomer concentrations in plasma and in pure fibrinogen solution. FDP at high concentrations inhibited ethanol gelation both in plasma and in pure fibrinogen solution. It is assumed that the phenomenon may, at least partly, provide an explanation of the frequent failure of the ethanol gelation test in case of disseminated intravascular clotting.
|Number of pages||6|
|Publication status||Published - dec. 1 1973|
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