Influence of cholecystokinin octapeptide sulfate ester on brain monoamine metabolism in rats

M. Fekete, T. Kádár, B. Penke, K. Kovács, G. Telegdy

Research output: Article

67 Citations (Scopus)

Abstract

The effects of intracerebroventricular administration of an 80 pmole dose of cholecystokinin octapeptide sulfate ester (CCK-8-SE) were tested on the dopamine (DA), norepinephrine (NE) and serotonin (5-HT) turnovers of the hypothalamus, mesencephalon, amygdala, septum, striatum and cerebral cortex in rats. CCK-8-SE in an 80 pmole dose decreased the DA turnovers of the hypothalamus, mesencephalon, amygdala and septum, while it increased that of the striatum. The NE turnovers were increased in the hypothalamus and amygdala, but decreased in the striatum. The 5-HT turnover decreased only in the hypothalamus.

Original languageEnglish
Pages (from-to)81-88
Number of pages8
JournalJournal of Neural Transmission
Volume50
Issue number2-4
DOIs
Publication statusPublished - jún. 1981

Fingerprint

Sincalide
Hypothalamus
Sulfates
Esters
Amygdala
Serotonin
Brain
Mesencephalon
Dopamine
Norepinephrine
Cerebral Cortex

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

Cite this

Influence of cholecystokinin octapeptide sulfate ester on brain monoamine metabolism in rats. / Fekete, M.; Kádár, T.; Penke, B.; Kovács, K.; Telegdy, G.

In: Journal of Neural Transmission, Vol. 50, No. 2-4, 06.1981, p. 81-88.

Research output: Article

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