Increased oxidative stress tolerance results in general stress tolerance in Candida albicans independently of stress-elicited morphological transitions

Ágnes Jakab, K. Antal, Ágnes Kiss, T. Emri, I. Pócsi

Research output: Article

4 Citations (Scopus)

Abstract

A selection of tert-butylhydroperoxide (tBOOH)-tolerant Candida albicans mutants showed increased tolerances to 19 different stress conditions. These mutants are characterized by a constitutively upregulated antioxidative defense system and, therefore, adaptation to oxidative stress may play an important role in gaining general stress tolerance in C. albicans. Although C. albicans cells may undergo morphological transitions under various stress treatments, this ability shows considerable stress-specific and strain-specific variability and, hence, it is independent of mounting stress cross protections.

Original languageEnglish
Pages (from-to)333-340
Number of pages8
JournalFolia Microbiologica
Volume59
Issue number4
DOIs
Publication statusPublished - 2014

Fingerprint

Candida albicans
Oxidative Stress
Cross Protection
tert-Butylhydroperoxide

ASJC Scopus subject areas

  • Microbiology
  • Medicine(all)

Cite this

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abstract = "A selection of tert-butylhydroperoxide (tBOOH)-tolerant Candida albicans mutants showed increased tolerances to 19 different stress conditions. These mutants are characterized by a constitutively upregulated antioxidative defense system and, therefore, adaptation to oxidative stress may play an important role in gaining general stress tolerance in C. albicans. Although C. albicans cells may undergo morphological transitions under various stress treatments, this ability shows considerable stress-specific and strain-specific variability and, hence, it is independent of mounting stress cross protections.",
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AU - Jakab, Ágnes

AU - Antal, K.

AU - Kiss, Ágnes

AU - Emri, T.

AU - Pócsi, I.

PY - 2014

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AB - A selection of tert-butylhydroperoxide (tBOOH)-tolerant Candida albicans mutants showed increased tolerances to 19 different stress conditions. These mutants are characterized by a constitutively upregulated antioxidative defense system and, therefore, adaptation to oxidative stress may play an important role in gaining general stress tolerance in C. albicans. Although C. albicans cells may undergo morphological transitions under various stress treatments, this ability shows considerable stress-specific and strain-specific variability and, hence, it is independent of mounting stress cross protections.

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JO - Folia Microbiologica

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