Inclusion body myositis - pathomechanism and lessons from genetics

Balázs Murnyák, Levente Bodoki, Melinda Vincze, Zoltán Griger, Tamás Csonka, Rita Szepesi, Andrea Kurucz, Katalin Dankó, Tibor Hortobágyi

Research output: Short survey

3 Citations (Scopus)


Inclusion body myositis is a rare, late-onset myopathy. Both inflammatory and myodegenerative features play an important role in their pathogenesis. Overlapping clinicopathological entities are the familial inclusion body myopathies with or without dementia. These myopathies share several clinical and pathological features with the sporadic inflammatory disease. Therefore, better understanding of the genetic basis and pathomechanism of these rare familial cases may advance our knowledge and enable more effective treatment options in sporadic IBM, which is currently considered a relentlessly progressive incurable disease.

Original languageEnglish
Pages (from-to)188-193
Number of pages6
JournalOpen Medicine (Poland)
Issue number1
Publication statusPublished - jan. 1 2015

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Inclusion body myositis - pathomechanism and lessons from genetics'. Together they form a unique fingerprint.

  • Cite this

    Murnyák, B., Bodoki, L., Vincze, M., Griger, Z., Csonka, T., Szepesi, R., Kurucz, A., Dankó, K., & Hortobágyi, T. (2015). Inclusion body myositis - pathomechanism and lessons from genetics. Open Medicine (Poland), 10(1), 188-193.