Impact of aneurysmal geometry on intraaneurysmal flow: A computerized flow simulation study

I. Szikora, Gyorgy Paal, Adam Ugron, Ferenc Nasztanovics, Miklos Marosfoi, Zsolt Berentei, Zsolt Kulcsar, Wickly Lee, Imre Bojtar, I. Nyáry

Research output: Article

42 Citations (Scopus)

Abstract

Introduction: This study was performed to assess the effect of aneurysm geometry on parameters that may have an impact on the natural history of intracranial aneurysms, such as intraaneurysmal flow pressure and shear stress. Methods: Flow was simulated in 21 randomly selected aneurysms using finite volume modeling. Ten aneurysms were classified as side-wall aneurysms, with either single-sided or circumferential involvement of the parent artery wall, and 11 as bifurcation aneurysms (symmetric or asymmetric), with an axis either perpendicular or parallel to the parent artery. The flow patterns were classified as either jet or vortex types (with regular or irregular vortex flow). Pressures and shear stresses were characterized as evenly or unevenly distributed over the aneurysm wall and neck. Results: All side-wall and four of the bifurcation aneurysms with a perpendicular axis had a vortex type flow pattern and seven bifurcation aneurysms with a parallel axis (four symmetric and two asymmetric) had a jet flow pattern. Jet type flow was associated with an uneven pressure distribution in seven out of seven aneurysms. Vortex type flow resulted in an even pressure distribution in five out of six aneurysms with an irregular flow pattern and six out of eight with a regular flow pattern. No firm relationship could be established between any geometrical type and shear stress distribution. Only 1 of 14 aneurysms with a perpendicular axis, but 4 of 7 aneurysms with a parallel axis, had ruptured. Conclusion: Aneurysm geometry does have an impact on flow conditions. Aneurysms with a main axis parallel to the parent artery have a tendency to have a jet flow pattern and uneven distribution of unsteady pressure. These aneurysms may have a higher rate of rupture as than those with a main axis perpendicular to the parent artery.

Original languageEnglish
Pages (from-to)411-421
Number of pages11
JournalNeuroradiology
Volume50
Issue number5
DOIs
Publication statusPublished - máj. 2008

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Aneurysm
Pressure
Arteries
Intracranial Aneurysm
Rupture
Neck

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Radiological and Ultrasound Technology

Cite this

Impact of aneurysmal geometry on intraaneurysmal flow : A computerized flow simulation study. / Szikora, I.; Paal, Gyorgy; Ugron, Adam; Nasztanovics, Ferenc; Marosfoi, Miklos; Berentei, Zsolt; Kulcsar, Zsolt; Lee, Wickly; Bojtar, Imre; Nyáry, I.

In: Neuroradiology, Vol. 50, No. 5, 05.2008, p. 411-421.

Research output: Article

Szikora, I, Paal, G, Ugron, A, Nasztanovics, F, Marosfoi, M, Berentei, Z, Kulcsar, Z, Lee, W, Bojtar, I & Nyáry, I 2008, 'Impact of aneurysmal geometry on intraaneurysmal flow: A computerized flow simulation study', Neuroradiology, vol. 50, no. 5, pp. 411-421. https://doi.org/10.1007/s00234-007-0350-x
Szikora, I. ; Paal, Gyorgy ; Ugron, Adam ; Nasztanovics, Ferenc ; Marosfoi, Miklos ; Berentei, Zsolt ; Kulcsar, Zsolt ; Lee, Wickly ; Bojtar, Imre ; Nyáry, I. / Impact of aneurysmal geometry on intraaneurysmal flow : A computerized flow simulation study. In: Neuroradiology. 2008 ; Vol. 50, No. 5. pp. 411-421.
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abstract = "Introduction: This study was performed to assess the effect of aneurysm geometry on parameters that may have an impact on the natural history of intracranial aneurysms, such as intraaneurysmal flow pressure and shear stress. Methods: Flow was simulated in 21 randomly selected aneurysms using finite volume modeling. Ten aneurysms were classified as side-wall aneurysms, with either single-sided or circumferential involvement of the parent artery wall, and 11 as bifurcation aneurysms (symmetric or asymmetric), with an axis either perpendicular or parallel to the parent artery. The flow patterns were classified as either jet or vortex types (with regular or irregular vortex flow). Pressures and shear stresses were characterized as evenly or unevenly distributed over the aneurysm wall and neck. Results: All side-wall and four of the bifurcation aneurysms with a perpendicular axis had a vortex type flow pattern and seven bifurcation aneurysms with a parallel axis (four symmetric and two asymmetric) had a jet flow pattern. Jet type flow was associated with an uneven pressure distribution in seven out of seven aneurysms. Vortex type flow resulted in an even pressure distribution in five out of six aneurysms with an irregular flow pattern and six out of eight with a regular flow pattern. No firm relationship could be established between any geometrical type and shear stress distribution. Only 1 of 14 aneurysms with a perpendicular axis, but 4 of 7 aneurysms with a parallel axis, had ruptured. Conclusion: Aneurysm geometry does have an impact on flow conditions. Aneurysms with a main axis parallel to the parent artery have a tendency to have a jet flow pattern and uneven distribution of unsteady pressure. These aneurysms may have a higher rate of rupture as than those with a main axis perpendicular to the parent artery.",
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T1 - Impact of aneurysmal geometry on intraaneurysmal flow

T2 - A computerized flow simulation study

AU - Szikora, I.

AU - Paal, Gyorgy

AU - Ugron, Adam

AU - Nasztanovics, Ferenc

AU - Marosfoi, Miklos

AU - Berentei, Zsolt

AU - Kulcsar, Zsolt

AU - Lee, Wickly

AU - Bojtar, Imre

AU - Nyáry, I.

PY - 2008/5

Y1 - 2008/5

N2 - Introduction: This study was performed to assess the effect of aneurysm geometry on parameters that may have an impact on the natural history of intracranial aneurysms, such as intraaneurysmal flow pressure and shear stress. Methods: Flow was simulated in 21 randomly selected aneurysms using finite volume modeling. Ten aneurysms were classified as side-wall aneurysms, with either single-sided or circumferential involvement of the parent artery wall, and 11 as bifurcation aneurysms (symmetric or asymmetric), with an axis either perpendicular or parallel to the parent artery. The flow patterns were classified as either jet or vortex types (with regular or irregular vortex flow). Pressures and shear stresses were characterized as evenly or unevenly distributed over the aneurysm wall and neck. Results: All side-wall and four of the bifurcation aneurysms with a perpendicular axis had a vortex type flow pattern and seven bifurcation aneurysms with a parallel axis (four symmetric and two asymmetric) had a jet flow pattern. Jet type flow was associated with an uneven pressure distribution in seven out of seven aneurysms. Vortex type flow resulted in an even pressure distribution in five out of six aneurysms with an irregular flow pattern and six out of eight with a regular flow pattern. No firm relationship could be established between any geometrical type and shear stress distribution. Only 1 of 14 aneurysms with a perpendicular axis, but 4 of 7 aneurysms with a parallel axis, had ruptured. Conclusion: Aneurysm geometry does have an impact on flow conditions. Aneurysms with a main axis parallel to the parent artery have a tendency to have a jet flow pattern and uneven distribution of unsteady pressure. These aneurysms may have a higher rate of rupture as than those with a main axis perpendicular to the parent artery.

AB - Introduction: This study was performed to assess the effect of aneurysm geometry on parameters that may have an impact on the natural history of intracranial aneurysms, such as intraaneurysmal flow pressure and shear stress. Methods: Flow was simulated in 21 randomly selected aneurysms using finite volume modeling. Ten aneurysms were classified as side-wall aneurysms, with either single-sided or circumferential involvement of the parent artery wall, and 11 as bifurcation aneurysms (symmetric or asymmetric), with an axis either perpendicular or parallel to the parent artery. The flow patterns were classified as either jet or vortex types (with regular or irregular vortex flow). Pressures and shear stresses were characterized as evenly or unevenly distributed over the aneurysm wall and neck. Results: All side-wall and four of the bifurcation aneurysms with a perpendicular axis had a vortex type flow pattern and seven bifurcation aneurysms with a parallel axis (four symmetric and two asymmetric) had a jet flow pattern. Jet type flow was associated with an uneven pressure distribution in seven out of seven aneurysms. Vortex type flow resulted in an even pressure distribution in five out of six aneurysms with an irregular flow pattern and six out of eight with a regular flow pattern. No firm relationship could be established between any geometrical type and shear stress distribution. Only 1 of 14 aneurysms with a perpendicular axis, but 4 of 7 aneurysms with a parallel axis, had ruptured. Conclusion: Aneurysm geometry does have an impact on flow conditions. Aneurysms with a main axis parallel to the parent artery have a tendency to have a jet flow pattern and uneven distribution of unsteady pressure. These aneurysms may have a higher rate of rupture as than those with a main axis perpendicular to the parent artery.

KW - Aneurysm geometry

KW - Aneurysm natural history

KW - Computational fluid dynamics

KW - Flow simulation

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