Hydrogenation of (±)-trans-2-arylnitrocyclohexane derivatives over palladium

Gábor Szántó, István Kádas, Tamás Kárpáti, László Hegedűs

Research output: Article

5 Citations (Scopus)

Abstract

Various (±)-trans-2-arylnitrocyclohexane derivatives were hydrogenated to the corresponding amines over a Pd/C catalyst in methanol at 25-60 °C and 1-12 bar. These (±)-trans-2-arylcyclohexylamines are important and valuable key intermediates for the stereoselective synthesis of phenantridine-based Amaryllidaceae alkaloid analogues having cytostatic activity.

Original languageEnglish
Pages (from-to)85-92
Number of pages8
JournalReaction Kinetics, Mechanisms and Catalysis
Volume99
Issue number1
DOIs
Publication statusPublished - febr. 2010

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry

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