Hydrogenation of pyrrole derivatives I. Hydrogenations over palladium

L. Hegedûs, Tibor Máthé, A. Tungler

Research output: Article

19 Citations (Scopus)

Abstract

The heterogeneous catalytic hydrogenation of 1-methyl-2-pyrrole ethanol resulted in 1-methyl-2-pyrrolidine ethanol, an important and valuable pharmaceutical intermediate. In non-acidic medium, with carbon supported palladium catalyst, applying solvent mixtures and mild reaction conditions (6 bar, 80°C) high conversion and selectivity were obtained. This hydrogenation is part of a newly developed and industrially feasible synthesis.

Original languageEnglish
Pages (from-to)309-316
Number of pages8
JournalApplied Catalysis A: General
Volume143
Issue number2
DOIs
Publication statusPublished - aug. 28 1996

Fingerprint

Pyrroles
Palladium
Hydrogenation
Ethanol
Derivatives
Drug products
Carbon
Catalysts
Pharmaceutical Preparations
pyrrolidine

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology

Cite this

Hydrogenation of pyrrole derivatives I. Hydrogenations over palladium. / Hegedûs, L.; Máthé, Tibor; Tungler, A.

In: Applied Catalysis A: General, Vol. 143, No. 2, 28.08.1996, p. 309-316.

Research output: Article

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