75 patients (28 HBsAG-positive and 28 HBsAg-negative) with chronic active hepatitis (CAH) were studied for HLA antigens. In the whole material, the HLA antigens were distributed as in the controls, with only the exception of the HLA-A9 antigen, the frequency of which, as compared with the controls, was moderately increased (37.4% against 22.7%). It was mainly the HBsAg-negative group which showed a significant increase in the frequency of the HLA-A9 antigen (42.9%). In the HBsAg-negative group, as compared with the HbsAg-positive group, where the frequency of HLA-A2 was 53.2% - and as compared with the controls, too - it was relatively low 29.3%. The frequency of HLA-A1 and HLA-B8 was not increased in any type of chronic active hepatitis. HLA-B8 was less frequent in the HBsAG-positive than in the HBsAG-negative group (10.6% against 21.4%).
|Number of pages||8|
|Journal||Acta medica Academiae Scientiarum Hungaricae|
|Publication status||Published - dec. 1 1980|
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