High performing rats are more sensitive toward catecholaminergic activity enhancer (CAE) compounds than their low performing peers

J. Knoll, Berta Knoll, Ildikó Miklya

Research output: Article

15 Citations (Scopus)

Abstract

Two breeds of rats, Charles River Wistar [Crl (Wi) Br.] and HSD Wistar [Wistar per LATI (Budapest) Br.], with remarkable difference in learning performance were selected. The rats were trained in the shuttle box with 100 trials per day and the number of conditioned avoidance responses (CARs), the escape failures (EFs) to the unconditioned stimulus and the intersignal reactions (IRs) were counted and evaluated by multi-way analysis of variance (ANOVA). Rats of the Crl (Wi) breed proved to be the 'low performing' (LP) animals and rats of the Wistar per LATI (Budapest) breed the 'high performing' (HP) ones. The HP rats produced higher number of CARs (p

Original languageEnglish
Pages (from-to)945-952
Number of pages8
JournalLife Sciences
Volume58
Issue number11
DOIs
Publication statusPublished - febr. 9 1996

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Rats
Rivers
Wistar Rats
Analysis of Variance
Analysis of variance (ANOVA)
Learning
Animals

ASJC Scopus subject areas

  • Pharmacology

Cite this

High performing rats are more sensitive toward catecholaminergic activity enhancer (CAE) compounds than their low performing peers. / Knoll, J.; Knoll, Berta; Miklya, Ildikó.

In: Life Sciences, Vol. 58, No. 11, 09.02.1996, p. 945-952.

Research output: Article

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