Hepatic steatosis in individuals living with HIV measured by controlled attenuation parameter: A cross-sectional study

Mihály Sulyok, Mihály Makara, Zsófia Rupnik, Tamás Ferenci, E. Újhelyi, Luca Kormos, Zsuzsanna Gerlei, János Szlávik, Gábor Horváth, István Vályi-Nagy

Research output: Article

16 Citations (Scopus)

Abstract

Objectives Available data on the prevalence of hepatic steatosis in an unselected HIV-infected population are limited. The aim of this study was to determine the prevalence of hepatic steatosis and assess the associated factors in HIV-infected individuals. Patients and methods One hundred and thirty-six HIV-infected individuals were enrolled in this cross-sectional study. Patients underwent transient elastography and controlled attenuation parameter (CAP) measurements. We analyzed the associations between the CAP value and demographic, metabolic, and immunologic parameters. For the first time, in HIV-infected individuals, we used a continuous scale of CAP values to identify significant covariates of hepatic fat accumulation. As a result and compared with other methods, one of the main advantages of CAP was that the quantitative measurement of liver steatosis could be used for analysis. Results Using univariate analysis, CAP was significantly correlated with the following continuous variables: CD4 percentage (P=0.035), CD8 percentage (P=0.016), age (P

Original languageEnglish
Pages (from-to)679-685
Number of pages7
JournalEuropean Journal of Gastroenterology and Hepatology
Volume27
Issue number6
DOIs
Publication statusPublished - dec. 1 2015

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology
  • Medicine(all)

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