Haemodynamics of cardiac arrest and resuscitation

P. Andréka, Michael P. Frenneaux

Research output: Article

61 Citations (Scopus)

Abstract

PURPOSE OF REVIEW: This review will summarize the available data regarding the haemodynamic changes occurring following cardiac arrest in humans and animal models. RECENT FINDINGS: Following cardiac arrest due to ventricular fibrillation without cardiopulmonary resuscitation, blood flow exponentially falls but continues for approximately 5 min until the pressure gradient between the aorta and the right heart is completely dissipated. During cardiopulmonary resuscitation forward flow occurs into the aorta during the compression phase. Coronary blood flow is retrograde during the compression phase and antegrade during the decompression phase. Carotid blood flow takes over a minute to reach plateau levels following the initiation of chest compressions, and even brief interruptions of compressions result in a dramatic reduction in carotid blood flow which takes a minute or so to recover to plateau levels when compressions are reinstituted. Coronary perfusion pressure during the release phase of cardiopulmonary resuscitation has been shown to be a powerful predictor of the likelihood of recovery of spontaneous circulation following restoration of electrical activity. SUMMARY: Recent studies have provided important insights into the haemodynamics of cardiac arrest and of cardiopulmonary resuscitation which may inform more effective strategies for the management of cardiac arrest in the future.

Original languageEnglish
Pages (from-to)198-203
Number of pages6
JournalCurrent Opinion in Critical Care
Volume12
Issue number3
DOIs
Publication statusPublished - jún. 2006

Fingerprint

Cardiopulmonary Resuscitation
Heart Arrest
Resuscitation
Hemodynamics
Aorta
Pressure
Ventricular Fibrillation
Decompression
Thorax
Animal Models
Perfusion

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Haemodynamics of cardiac arrest and resuscitation. / Andréka, P.; Frenneaux, Michael P.

In: Current Opinion in Critical Care, Vol. 12, No. 3, 06.2006, p. 198-203.

Research output: Article

Andréka, P. ; Frenneaux, Michael P. / Haemodynamics of cardiac arrest and resuscitation. In: Current Opinion in Critical Care. 2006 ; Vol. 12, No. 3. pp. 198-203.
@article{f516e475da11473697f1390a3fd369e7,
title = "Haemodynamics of cardiac arrest and resuscitation",
abstract = "PURPOSE OF REVIEW: This review will summarize the available data regarding the haemodynamic changes occurring following cardiac arrest in humans and animal models. RECENT FINDINGS: Following cardiac arrest due to ventricular fibrillation without cardiopulmonary resuscitation, blood flow exponentially falls but continues for approximately 5 min until the pressure gradient between the aorta and the right heart is completely dissipated. During cardiopulmonary resuscitation forward flow occurs into the aorta during the compression phase. Coronary blood flow is retrograde during the compression phase and antegrade during the decompression phase. Carotid blood flow takes over a minute to reach plateau levels following the initiation of chest compressions, and even brief interruptions of compressions result in a dramatic reduction in carotid blood flow which takes a minute or so to recover to plateau levels when compressions are reinstituted. Coronary perfusion pressure during the release phase of cardiopulmonary resuscitation has been shown to be a powerful predictor of the likelihood of recovery of spontaneous circulation following restoration of electrical activity. SUMMARY: Recent studies have provided important insights into the haemodynamics of cardiac arrest and of cardiopulmonary resuscitation which may inform more effective strategies for the management of cardiac arrest in the future.",
keywords = "Cardiac arrest, Cardiopulmonary resuscitation, Haemodynamics, Recovery of spontaneous circulation",
author = "P. Andr{\'e}ka and Frenneaux, {Michael P.}",
year = "2006",
month = "6",
doi = "10.1097/01.ccx.0000224861.70958.59",
language = "English",
volume = "12",
pages = "198--203",
journal = "Current Opinion in Critical Care",
issn = "1070-5295",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Haemodynamics of cardiac arrest and resuscitation

AU - Andréka, P.

AU - Frenneaux, Michael P.

PY - 2006/6

Y1 - 2006/6

N2 - PURPOSE OF REVIEW: This review will summarize the available data regarding the haemodynamic changes occurring following cardiac arrest in humans and animal models. RECENT FINDINGS: Following cardiac arrest due to ventricular fibrillation without cardiopulmonary resuscitation, blood flow exponentially falls but continues for approximately 5 min until the pressure gradient between the aorta and the right heart is completely dissipated. During cardiopulmonary resuscitation forward flow occurs into the aorta during the compression phase. Coronary blood flow is retrograde during the compression phase and antegrade during the decompression phase. Carotid blood flow takes over a minute to reach plateau levels following the initiation of chest compressions, and even brief interruptions of compressions result in a dramatic reduction in carotid blood flow which takes a minute or so to recover to plateau levels when compressions are reinstituted. Coronary perfusion pressure during the release phase of cardiopulmonary resuscitation has been shown to be a powerful predictor of the likelihood of recovery of spontaneous circulation following restoration of electrical activity. SUMMARY: Recent studies have provided important insights into the haemodynamics of cardiac arrest and of cardiopulmonary resuscitation which may inform more effective strategies for the management of cardiac arrest in the future.

AB - PURPOSE OF REVIEW: This review will summarize the available data regarding the haemodynamic changes occurring following cardiac arrest in humans and animal models. RECENT FINDINGS: Following cardiac arrest due to ventricular fibrillation without cardiopulmonary resuscitation, blood flow exponentially falls but continues for approximately 5 min until the pressure gradient between the aorta and the right heart is completely dissipated. During cardiopulmonary resuscitation forward flow occurs into the aorta during the compression phase. Coronary blood flow is retrograde during the compression phase and antegrade during the decompression phase. Carotid blood flow takes over a minute to reach plateau levels following the initiation of chest compressions, and even brief interruptions of compressions result in a dramatic reduction in carotid blood flow which takes a minute or so to recover to plateau levels when compressions are reinstituted. Coronary perfusion pressure during the release phase of cardiopulmonary resuscitation has been shown to be a powerful predictor of the likelihood of recovery of spontaneous circulation following restoration of electrical activity. SUMMARY: Recent studies have provided important insights into the haemodynamics of cardiac arrest and of cardiopulmonary resuscitation which may inform more effective strategies for the management of cardiac arrest in the future.

KW - Cardiac arrest

KW - Cardiopulmonary resuscitation

KW - Haemodynamics

KW - Recovery of spontaneous circulation

UR - http://www.scopus.com/inward/record.url?scp=33748538650&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748538650&partnerID=8YFLogxK

U2 - 10.1097/01.ccx.0000224861.70958.59

DO - 10.1097/01.ccx.0000224861.70958.59

M3 - Article

C2 - 16672776

AN - SCOPUS:33748538650

VL - 12

SP - 198

EP - 203

JO - Current Opinion in Critical Care

JF - Current Opinion in Critical Care

SN - 1070-5295

IS - 3

ER -