Genetic characterization of a second novel picornavirus from an amphibian host, smooth newt (Lissotriton vulgaris)

Péter Pankovics, Ákos Boros, Zoltán Tóth, Tung Gia Phan, Eric Delwart, G. Reuter

Research output: Article

3 Citations (Scopus)

Abstract

In this study, a novel picornavirus was identified in faecal samples from smooth newts (Lissotriton vulgaris). The complete genome of picornavirus strain newt/II-5-Pilis/2014/HUN (KX463670) is 7755 nt long with type-IV IRES and has 39.6% aa sequence identity in the protein P1 to the corresponding protein of bat picornavirus (KJ641686, unassigned) and 42.7% and 53.5% aa sequence identity in the 2C and 3CD protein, respectively, to oscivirus (GU182410, genus Oscivirus). Interestingly, the L-protein of newt/II-5-Pilis/2014/HUN has conserved aa motifs that are similar to those found in phosphatase-1 catalytic (PP1C) subunit binding region (pfam10488) proteins. This second amphibian-origin picornavirus could represent a novel species and could be a founding member of a potential novel picornavirus genus.

Original languageEnglish
Pages (from-to)1043-1050
Number of pages8
JournalArchives of Virology
Volume162
Issue number4
DOIs
Publication statusPublished - ápr. 1 2017

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Picornaviridae
Salamandridae
Amphibians
Proteins
Phosphoric Monoester Hydrolases
Catalytic Domain
Genome

ASJC Scopus subject areas

  • Virology

Cite this

Genetic characterization of a second novel picornavirus from an amphibian host, smooth newt (Lissotriton vulgaris). / Pankovics, Péter; Boros, Ákos; Tóth, Zoltán; Phan, Tung Gia; Delwart, Eric; Reuter, G.

In: Archives of Virology, Vol. 162, No. 4, 01.04.2017, p. 1043-1050.

Research output: Article

Pankovics, Péter ; Boros, Ákos ; Tóth, Zoltán ; Phan, Tung Gia ; Delwart, Eric ; Reuter, G. / Genetic characterization of a second novel picornavirus from an amphibian host, smooth newt (Lissotriton vulgaris). In: Archives of Virology. 2017 ; Vol. 162, No. 4. pp. 1043-1050.
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