Four spatial points that define enzyme families

Gábor Iván, Zoltán Szabadka, Rafael Ördög, Vince Grolmusz, G. Náray-Szabó

Research output: Article

7 Citations (Scopus)

Abstract

The catalytic properties of enzymes, containing the Asp-His-Ser triads are deeply investigated for a long time. Serine endopeptidases, cutinases, acetylcholinesterases, cellulases, among other enzymes, contain these triads. We found that solely the geometric properties of just four points in the spatial structure of these enzymes are characteristic to their family (Fig. 3).

Original languageEnglish
Pages (from-to)417-420
Number of pages4
JournalBiochemical and Biophysical Research Communications
Volume383
Issue number4
DOIs
Publication statusPublished - jún. 12 2009

Fingerprint

Serine Endopeptidases
Enzymes
Cellulases
Acetylcholinesterase
cutinase

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Cell Biology
  • Molecular Biology

Cite this

Four spatial points that define enzyme families. / Iván, Gábor; Szabadka, Zoltán; Ördög, Rafael; Grolmusz, Vince; Náray-Szabó, G.

In: Biochemical and Biophysical Research Communications, Vol. 383, No. 4, 12.06.2009, p. 417-420.

Research output: Article

Iván, Gábor ; Szabadka, Zoltán ; Ördög, Rafael ; Grolmusz, Vince ; Náray-Szabó, G. / Four spatial points that define enzyme families. In: Biochemical and Biophysical Research Communications. 2009 ; Vol. 383, No. 4. pp. 417-420.
@article{bbc1791ad3674c409613f2c64baf135d,
title = "Four spatial points that define enzyme families",
abstract = "The catalytic properties of enzymes, containing the Asp-His-Ser triads are deeply investigated for a long time. Serine endopeptidases, cutinases, acetylcholinesterases, cellulases, among other enzymes, contain these triads. We found that solely the geometric properties of just four points in the spatial structure of these enzymes are characteristic to their family (Fig. 3).",
keywords = "Catalytic triad, Data mining, Protein Data Bank",
author = "G{\'a}bor Iv{\'a}n and Zolt{\'a}n Szabadka and Rafael {\"O}rd{\"o}g and Vince Grolmusz and G. N{\'a}ray-Szab{\'o}",
year = "2009",
month = "6",
day = "12",
doi = "10.1016/j.bbrc.2009.04.022",
language = "English",
volume = "383",
pages = "417--420",
journal = "Biochemical and Biophysical Research Communications",
issn = "0006-291X",
publisher = "Academic Press Inc.",
number = "4",

}

TY - JOUR

T1 - Four spatial points that define enzyme families

AU - Iván, Gábor

AU - Szabadka, Zoltán

AU - Ördög, Rafael

AU - Grolmusz, Vince

AU - Náray-Szabó, G.

PY - 2009/6/12

Y1 - 2009/6/12

N2 - The catalytic properties of enzymes, containing the Asp-His-Ser triads are deeply investigated for a long time. Serine endopeptidases, cutinases, acetylcholinesterases, cellulases, among other enzymes, contain these triads. We found that solely the geometric properties of just four points in the spatial structure of these enzymes are characteristic to their family (Fig. 3).

AB - The catalytic properties of enzymes, containing the Asp-His-Ser triads are deeply investigated for a long time. Serine endopeptidases, cutinases, acetylcholinesterases, cellulases, among other enzymes, contain these triads. We found that solely the geometric properties of just four points in the spatial structure of these enzymes are characteristic to their family (Fig. 3).

KW - Catalytic triad

KW - Data mining

KW - Protein Data Bank

UR - http://www.scopus.com/inward/record.url?scp=67349173163&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67349173163&partnerID=8YFLogxK

U2 - 10.1016/j.bbrc.2009.04.022

DO - 10.1016/j.bbrc.2009.04.022

M3 - Article

C2 - 19364497

AN - SCOPUS:67349173163

VL - 383

SP - 417

EP - 420

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

IS - 4

ER -