Five unique compounds: Xyloketals from mangrove fungus Xylaria sp. from the South China Sea coast

Y. Lin, X. Wu, S. Feng, G. Jiang, J. Luo, S. Zhou, L. L.P. Vrijmoed, E. B.G. Jones, K. Krohn, K. Steingröver, F. Zsila

Research output: Article

251 Citations (Scopus)

Abstract

Five unique metabolites, xyloketals A (1), B (2), C (3), D (4), and E (5), and the known 6 were isolated from mangrove fungus Xylaria sp. (no. 2508), obtained from the South China Sea. The structures of these compounds were elucidated by spectroscopic and X-ray diffraction experiments. Xyloketal A is a ketal compound with a C3 symmetry and xyloketals B-E are its analogues. It was found that xytoketal C slowly rearranged to xytoketal B in DMSO-d6 solution at room temperature. Xyloketal A exhibited the activity of inhibiting acetylcholine esterase.

Original languageEnglish
Pages (from-to)6252-6256
Number of pages5
JournalJournal of Organic Chemistry
Volume66
Issue number19
DOIs
Publication statusPublished - szept. 21 2001

ASJC Scopus subject areas

  • Organic Chemistry

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    Lin, Y., Wu, X., Feng, S., Jiang, G., Luo, J., Zhou, S., Vrijmoed, L. L. P., Jones, E. B. G., Krohn, K., Steingröver, K., & Zsila, F. (2001). Five unique compounds: Xyloketals from mangrove fungus Xylaria sp. from the South China Sea coast. Journal of Organic Chemistry, 66(19), 6252-6256. https://doi.org/10.1021/jo015522r