Koi herpes virus was first described in Europe in 1998. The first outbreaks in Hungary were noted in 2012 (n = 2) and 2013 (n = 3). Most of the diseased fish showed necrotic changes and haemorrhagic patches on gills and some of them enlargement of spleen. Histopathological examination revealed hyperplasia and hypertrophy of branchial epithelium and fusion of secondary lamellae. These findings were most pronounced at the top of lamellae. Necrotic areas were also detected. Occasionally the branchial epithelial cells had nuclear swelling, margination of chromatin to give a "signet ring" appearance and eosinophilic intranuclear inclusions were observed. Diagnosis of the disease was based on pathological and histopathological findings and confirmed by PCR and sequencing. The mortality rates in the Hungarian outbreaks were considerably lower (< 35%) than described the literature.
|Number of pages||7|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - dec. 1 2014|
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