Felszilard gyogyszerformak gyogyszerleadasat befolyasolo tenyezok

I. Erös, J. A. Ehab, A. Cserne, I. Csoka, E. Csanyi

Research output: Article

5 Citations (Scopus)

Abstract

Liberation of salicylic acid - as a model active agent - was investigated from white petrolatum, creams w/o and o/w types and hydrogels. Active agent was applied in suspended, dissolved forms, in inclusion complexes and solubilized state. The process of liberation was studied by a continuous through-flow method, with Hanson vertical diffusion cell. The results of experiments were evaluated by factorial design method. Increase of the concentration of salicylic acid, polarity of vehicle and solubilized state of drug increased the drug release. It was established that the partitioning released drug was the most important step of drug release. Factors changing partitioning influenced the liberation to the highest degree.

Original languageHungarian
Pages (from-to)29-34
Number of pages6
JournalActa Pharmaceutica Hungarica
Volume70
Issue number2
Publication statusPublished - 2000

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Salicylic Acid
Dosage Forms
Petrolatum
Hydrogels
Pharmaceutical Preparations
Drug Liberation

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Erös, I., Ehab, J. A., Cserne, A., Csoka, I., & Csanyi, E. (2000). Felszilard gyogyszerformak gyogyszerleadasat befolyasolo tenyezok. Acta Pharmaceutica Hungarica, 70(2), 29-34.

Felszilard gyogyszerformak gyogyszerleadasat befolyasolo tenyezok. / Erös, I.; Ehab, J. A.; Cserne, A.; Csoka, I.; Csanyi, E.

In: Acta Pharmaceutica Hungarica, Vol. 70, No. 2, 2000, p. 29-34.

Research output: Article

Erös, I, Ehab, JA, Cserne, A, Csoka, I & Csanyi, E 2000, 'Felszilard gyogyszerformak gyogyszerleadasat befolyasolo tenyezok', Acta Pharmaceutica Hungarica, vol. 70, no. 2, pp. 29-34.
Erös, I. ; Ehab, J. A. ; Cserne, A. ; Csoka, I. ; Csanyi, E. / Felszilard gyogyszerformak gyogyszerleadasat befolyasolo tenyezok. In: Acta Pharmaceutica Hungarica. 2000 ; Vol. 70, No. 2. pp. 29-34.
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