Exploitation of Feedback in Enzyme-catalysed Reactions

T. Bánsági, Annette F. Taylor

Research output: Article

Abstract

Some cellular systems, such as yeast, bacteria and slime mould, display dynamic behavior including switches and rhythms driven by feedback in enzyme-catalysed reactions. The mechanisms of these processes have been well investigated and recent attention has turned to generating similar responses in synthetic biocatalytic systems, with a view to creating bioinspired analogues for applications. Here we discuss how feedback arises in the reaction mechanisms of some enzyme-catalyzed reactions invitro, the behaviour obtained and the emerging applications. These autocatalytic reactions may provide insights into behaviour in cellular systems as well as new methods for drug delivery, sensing and repair that can be exploited in living systems.

Original languageEnglish
JournalIsrael Journal of Chemistry
DOIs
Publication statusAccepted/In press - jan. 1 2018

Fingerprint

Feedback
Enzymes
Drug delivery
Yeast
Bacteria
Repair
Switches

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Exploitation of Feedback in Enzyme-catalysed Reactions. / Bánsági, T.; Taylor, Annette F.

In: Israel Journal of Chemistry, 01.01.2018.

Research output: Article

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