Experimental study of hormone receptor development in a unicellular model system

G. Csaba, G. Nemeth, P. Vargha

Research output: Article

1 Citation (Scopus)

Abstract

It was shown earlier that diiodotyrosine (T2) stimulates the growth of Tetrahymena. In the present study clonal populations of Tetrahymen, derived from subcultures propagated in the presence of T2, showed a highly significant increase of intra-clone variance over the control, while inter-clone variation was significant, but not decisive. This suggests that genetic factors play a smaller role in the development of the cell membrane receptor pattern than the genetic variability of the membrane itself, which seems to account for the stabilization of the adequate receptors on first exposure to a hormone.

Original languageEnglish
Pages (from-to)173-176
Number of pages4
JournalExperimental Cell Biology
Volume49
Issue number3
Publication statusPublished - 1981

Fingerprint

Diiodotyrosine
Clone Cells
Hormones
Tetrahymena
Cell Membrane
Membranes
Growth
Population

ASJC Scopus subject areas

  • Cell Biology

Cite this

@article{a79310b1f26a46dc883fad8f8cdaef7f,
title = "Experimental study of hormone receptor development in a unicellular model system",
abstract = "It was shown earlier that diiodotyrosine (T2) stimulates the growth of Tetrahymena. In the present study clonal populations of Tetrahymen, derived from subcultures propagated in the presence of T2, showed a highly significant increase of intra-clone variance over the control, while inter-clone variation was significant, but not decisive. This suggests that genetic factors play a smaller role in the development of the cell membrane receptor pattern than the genetic variability of the membrane itself, which seems to account for the stabilization of the adequate receptors on first exposure to a hormone.",
author = "G. Csaba and G. Nemeth and P. Vargha",
year = "1981",
language = "English",
volume = "49",
pages = "173--176",
journal = "Pathobiology",
issn = "1015-2008",
publisher = "S. Karger AG",
number = "3",

}

TY - JOUR

T1 - Experimental study of hormone receptor development in a unicellular model system

AU - Csaba, G.

AU - Nemeth, G.

AU - Vargha, P.

PY - 1981

Y1 - 1981

N2 - It was shown earlier that diiodotyrosine (T2) stimulates the growth of Tetrahymena. In the present study clonal populations of Tetrahymen, derived from subcultures propagated in the presence of T2, showed a highly significant increase of intra-clone variance over the control, while inter-clone variation was significant, but not decisive. This suggests that genetic factors play a smaller role in the development of the cell membrane receptor pattern than the genetic variability of the membrane itself, which seems to account for the stabilization of the adequate receptors on first exposure to a hormone.

AB - It was shown earlier that diiodotyrosine (T2) stimulates the growth of Tetrahymena. In the present study clonal populations of Tetrahymen, derived from subcultures propagated in the presence of T2, showed a highly significant increase of intra-clone variance over the control, while inter-clone variation was significant, but not decisive. This suggests that genetic factors play a smaller role in the development of the cell membrane receptor pattern than the genetic variability of the membrane itself, which seems to account for the stabilization of the adequate receptors on first exposure to a hormone.

UR - http://www.scopus.com/inward/record.url?scp=0019419976&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019419976&partnerID=8YFLogxK

M3 - Article

C2 - 6265301

AN - SCOPUS:0019419976

VL - 49

SP - 173

EP - 176

JO - Pathobiology

JF - Pathobiology

SN - 1015-2008

IS - 3

ER -