Background: The effects of vaginal delivery (VD) and of cesarean section (CS) on the markers of oxidative stress were investigated. Materials and Methods: Umbilical blood samples were analyzed from 74 full-term neonates, 46 born via VD, 28 via elective CS. The level of lipid peroxidation (LP), protein and DNA damage and the antioxidant status were compared. Results: Differences between CS and VD groups were generally non-significant for oxidative markers, except for the GSH concentrations (VD: 4.18 vs. CS: 2.77 μM/mg protein x 10-3; p<0.05). LP was significantly higher in the CS group (0.078 vs. 0.042 nM MDA/mg protein; p<0.05). The level of carbonyl proteins was high in the VD group and significantly lower in the elective CS group (9.5 vs. 8.1 mM/mg protein x 10-4; p<0.05). We found 0.78% more strand breaks in elective CS group than in VD group. Conclusion: CS does not have an advantage over VD with respect to oxidative stress.
|Number of pages||4|
|Publication status||Published - júl. 1 2007|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)