Az enalapril hatékonysága a kutyák pangásos szívelégtelenségének gyógykezelésében

K. Vörös, Vrabély Tamás, Manczur Ferenc, Szatmári Viktor

Research output: Article

2 Citations (Scopus)

Abstract

Efficacy of enalapril (Cardiovet A.U.V.) was studied in 18 dogs suffering from chronic congestive cardiac failure. History was recorded and baseline physical examinations were performed. Patients were classified according to the category of congestive cardiac failure (Fig. 1). Cardiological diagnoses were based on ECG and echocardiographic examinations (Fig. 2 and 3). The latter included both two-dimensional and M-mode echocardiography which surved for measurement of left ventricular dimensions, as well as for calculations of fractional shortening. Patients received enalapril per os in a dosis of 0.5 mg/bwkg/24 hours. Occasionaly further drugs used in congestive cardiac failure (e.g. furosemide, digoxin) and antiarrhythmic drugs (verapamil) were added to enalapril treatment. Controll examinations (including physical examinations, ECG and echocardiography) were performed one and four weeks after initiating medical therapy. Several breeds were represented in the population of the 18 dogs, and 10 (55.6%) suffered from chronic endocardiosis, 6 (33.3%) from dilated cardiomyopathy and 2 (11.1%) had chronic endocarditis. By the time of the second examination (after one week) 13 dogs (72.1%) showed improvement of the cardiac failure (Table 1), whilst 3 patients (16.7%) did not improve. One dog (5.6%) was not referred to the second appointment and one (5.6%) has died by that time. During the third examination (after four weeks) 14 patients (77.7%) improved, one dog (5.6%) was not taken for the examination, and two dogs (11.1%) have died due to the worsening of the congestive cardiac failure. Table 2 demonstrates the results of treatment, according to the categories of cardiac insufficiency at the time of the baseline examinations and on the fourth week, respectively. Improvement of congestive cardiac insufficiency can be mainly explained by the beneficial effects of enalapril as 22.2% of the dogs have received solely this drog, 47.4% of them were treated with enalapril and diuretics and only 30.4% received additional digoxin treatment.

Original languageHungarian
Pages (from-to)274-280
Number of pages7
JournalMagyar Allatorvosok Lapja
Volume120
Issue number5
Publication statusPublished - 1998

Fingerprint

Enalapril
heart failure
Heart Failure
Dogs
dogs
digoxin
Digoxin
echocardiography
clinical examination
Therapeutics
Physical Examination
Echocardiography
Electrocardiography
furosemide
drugs
endocarditis
verapamil
diuretics
Anti-Arrhythmia Agents
cardiomyopathy

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Az enalapril hatékonysága a kutyák pangásos szívelégtelenségének gyógykezelésében. / Vörös, K.; Tamás, Vrabély; Ferenc, Manczur; Viktor, Szatmári.

In: Magyar Allatorvosok Lapja, Vol. 120, No. 5, 1998, p. 274-280.

Research output: Article

Vörös, K. ; Tamás, Vrabély ; Ferenc, Manczur ; Viktor, Szatmári. / Az enalapril hatékonysága a kutyák pangásos szívelégtelenségének gyógykezelésében. In: Magyar Allatorvosok Lapja. 1998 ; Vol. 120, No. 5. pp. 274-280.
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abstract = "Efficacy of enalapril (Cardiovet A.U.V.) was studied in 18 dogs suffering from chronic congestive cardiac failure. History was recorded and baseline physical examinations were performed. Patients were classified according to the category of congestive cardiac failure (Fig. 1). Cardiological diagnoses were based on ECG and echocardiographic examinations (Fig. 2 and 3). The latter included both two-dimensional and M-mode echocardiography which surved for measurement of left ventricular dimensions, as well as for calculations of fractional shortening. Patients received enalapril per os in a dosis of 0.5 mg/bwkg/24 hours. Occasionaly further drugs used in congestive cardiac failure (e.g. furosemide, digoxin) and antiarrhythmic drugs (verapamil) were added to enalapril treatment. Controll examinations (including physical examinations, ECG and echocardiography) were performed one and four weeks after initiating medical therapy. Several breeds were represented in the population of the 18 dogs, and 10 (55.6{\%}) suffered from chronic endocardiosis, 6 (33.3{\%}) from dilated cardiomyopathy and 2 (11.1{\%}) had chronic endocarditis. By the time of the second examination (after one week) 13 dogs (72.1{\%}) showed improvement of the cardiac failure (Table 1), whilst 3 patients (16.7{\%}) did not improve. One dog (5.6{\%}) was not referred to the second appointment and one (5.6{\%}) has died by that time. During the third examination (after four weeks) 14 patients (77.7{\%}) improved, one dog (5.6{\%}) was not taken for the examination, and two dogs (11.1{\%}) have died due to the worsening of the congestive cardiac failure. Table 2 demonstrates the results of treatment, according to the categories of cardiac insufficiency at the time of the baseline examinations and on the fourth week, respectively. Improvement of congestive cardiac insufficiency can be mainly explained by the beneficial effects of enalapril as 22.2{\%} of the dogs have received solely this drog, 47.4{\%} of them were treated with enalapril and diuretics and only 30.4{\%} received additional digoxin treatment.",
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