Effects of mixed neutron-gamma irradiation in vivo on the cell surfaces of murine blood cells

Tamara Kubasova, Sára Antal, Z. Somosy, G. J. Köteles

Research output: Article

10 Citations (Scopus)

Abstract

For studies on cell membranes, mice were exposed to mixed neutron + gamma reactor-radiation in the range of total doses from 0.5 to 4.5 Gy. Changes in functional activity of plasma membranes of erythrocytes, platelets, and lymphocytes were followed by a lectin-binding technique at various intervals afterwards. The amount of3H-concanavalin A bound to cells altered considerably during the 1st h after irradiation in all cell types. Lymphocytes and platelets, however, were more sensitive than erythrocytes as increased lectin-binding could already be observed after 0.5 Gy. The binding ability of these cells performed oscillatory behaviour. In addition, alterations in shapes and ultrastructure of cell surfaces and intracellular membranes were observed.

Original languageEnglish
Pages (from-to)269-277
Number of pages9
JournalRadiation and Environmental Biophysics
Volume23
Issue number4
DOIs
Publication statusPublished - dec. 1984

Fingerprint

blood cells
Lymphocytes
Neutrons
Cell membranes
Platelets
Lectins
gamma radiation
Blood Cells
irradiation
Blood
blood
Cells
Cell Membrane
Irradiation
membrane
neutrons
lymphocytes
mice
erythrocytes
Blood Platelets

ASJC Scopus subject areas

  • Radiation
  • Physics and Astronomy (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Environmental Chemistry
  • Environmental Science (miscellaneous)
  • Environmental Science(all)
  • Biophysics
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Effects of mixed neutron-gamma irradiation in vivo on the cell surfaces of murine blood cells. / Kubasova, Tamara; Antal, Sára; Somosy, Z.; Köteles, G. J.

In: Radiation and Environmental Biophysics, Vol. 23, No. 4, 12.1984, p. 269-277.

Research output: Article

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