DIE WIRKUNG VON FUROSEMID AUF DIE NIERENFUNKTION VON FRUHGEBORENEN MIT ATEMNOTSYNDROM

T. Tulassay, J. Kiszel, T. Machay, S. Csomor

Research output: Article

1 Citation (Scopus)

Abstract

Renal effects of furosemide were examined during the first 2-4 days of life in preterm infants suffering from respiratory distress syndrome. Administration of the drug was followed by a 7-fold increase of diuresis. This latter was a result of both a rise in sodium excretion and glomerular filtration. The possible mechanism of furosemide-induced alteration in the glomerular filtration is discussed. Furosemide also altered the hydrogen-ion excretion: both the urinary bicarbonate, the titratable acidity and the ammonium excretion increased. There was a significant rise in the net acid excretion and hydrogen clearance too. It has been found that besides its diuretic effect furosemide might play a role in the renal hydrogen elimination.

Original languageGerman
Pages (from-to)541-545
Number of pages5
JournalMonatsschrift fur Kinderheilkunde
Volume130
Issue number7
Publication statusPublished - jan. 1 1982

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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