Effect of the partial constriction of portal vein on renal hypertension in the rat

S. Sonkodi, L. Perényi, T. Zoltán

Research output: Article

3 Citations (Scopus)

Abstract

Partial constriction of the portal vein in the rat impedes the development of renal hypertension, or decreases the already developed hypertension, respectively. Taking into consideration the fact that this effect could be observed also in that experimental form (left kidney clipped, the opposite one removed) in which the renin content of the clipped kidney and the increase of plasma renin activity could never be demonstrated – and even in the other experimental form (left kidney clipped, the opposite one untouched) – the protective effect was only present when the above-mentioned increase of renin level was already normalized: it seems that the protective effect of partial constriction of the portal vein does not take place due to the possible hepatic damage leading to an angiotensinogen production in a lower degree.

Original languageEnglish
Pages (from-to)77-82
Number of pages6
JournalJournal of Vascular Research
Volume8
Issue number2
DOIs
Publication statusPublished - 1971

Fingerprint

Renal Hypertension
Portal Vein
Renin
Constriction
Kidney
Angiotensinogen
Hypertension
Liver

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Effect of the partial constriction of portal vein on renal hypertension in the rat. / Sonkodi, S.; Perényi, L.; Zoltán, T.

In: Journal of Vascular Research, Vol. 8, No. 2, 1971, p. 77-82.

Research output: Article

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