The aim of present study was to investigate whether garlic essential oil with natural organosulfur compounds that possess free radical scavenging activity is able to alleviate the adverse effects of T-2 toxin. In a two-weeks feeding trial with 14-day old Cobb cockerels (n=15 per group) housed in batteries, twelve experimental treatments were applied. The basal diet was experimentally contaminated with T-2 toxin at concentrations of 0, 0.52, 1.05 or 2.05 mg/kg and at each contamination level garlic oil was added at a dosage rate of 0, 0.3 or 1.5 g/kg, respectively. The experimental diets were fed for 14 days. In the first week of the trial, production traits showed numerically lower body weights, a lower feed intake, and subsequently higher feed to gain ratios in the animals exposed to T-2 toxin-contaminated diets. This effect became non-significant in the second week. Garlic oil supplementation at the lower dose of 0.3 mg/kg resulted in a significantly lower body weight gain at the highest T-2 toxin contamination level. The malondialdehyde concentration did not show any dose-related changes. The level of reduced glutathione was significantly higher in blood plasma as a result of the lower (0.3 g/kg) garlic oil supplementation and as an effect of T-2 toxin challenge in red blood cell haemolysate. Glutathione peroxidase activity showed the same trend. The results showed that the lower (0.3 g/kg) but not the higher (1.5 g/kg) dose of garlic oil supplementation had desirable effects on the measured redox parameters, eliminating some of the adverse effects of feeding T-2 toxin contaminated diet.
ASJC Scopus subject areas
- Food Science
- Public Health, Environmental and Occupational Health