Effect of endotoxin on placental metabolism. Experimental study on the influence of infections with gram-negative bacteria during pregnancy

E. Czeizel, M. Sajgó, Gy Tarján, P. Kertai

Research output: Article

3 Citations (Scopus)

Abstract

An inhibition of aerobic glycolysis in the placental tissue of rat was demonstrable one hour after administration of endotoxin and was still present after 48 hours. However, oxygen uptake of the placental tissue remained unchanged. The RNA content of the placenta decreased notably after fetal death. It is supposed that the role of gram-negative bacteria in pathology of pregnancy is brought about by the inhibition of placental metabolism by the action of their endotoxin.

Original languageEnglish
Pages (from-to)1129-1134
Number of pages6
JournalAmerican Journal of Obstetrics and Gynecology
Volume98
Issue number8
Publication statusPublished - aug. 15 1967

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Medicine(all)

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