Abstract
An inhibition of aerobic glycolysis in the placental tissue of rat was demonstrable one hour after administration of endotoxin and was still present after 48 hours. However, oxygen uptake of the placental tissue remained unchanged. The RNA content of the placenta decreased notably after fetal death. It is supposed that the role of gram-negative bacteria in pathology of pregnancy is brought about by the inhibition of placental metabolism by the action of their endotoxin.
Original language | English |
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Pages (from-to) | 1129-1134 |
Number of pages | 6 |
Journal | American Journal of Obstetrics and Gynecology |
Volume | 98 |
Issue number | 8 |
Publication status | Published - aug. 15 1967 |
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ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Medicine(all)
Cite this
Effect of endotoxin on placental metabolism. Experimental study on the influence of infections with gram-negative bacteria during pregnancy. / Czeizel, E.; Sajgó, M.; Tarján, Gy; Kertai, P.
In: American Journal of Obstetrics and Gynecology, Vol. 98, No. 8, 15.08.1967, p. 1129-1134.Research output: Article
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TY - JOUR
T1 - Effect of endotoxin on placental metabolism. Experimental study on the influence of infections with gram-negative bacteria during pregnancy
AU - Czeizel, E.
AU - Sajgó, M.
AU - Tarján, Gy
AU - Kertai, P.
PY - 1967/8/15
Y1 - 1967/8/15
N2 - An inhibition of aerobic glycolysis in the placental tissue of rat was demonstrable one hour after administration of endotoxin and was still present after 48 hours. However, oxygen uptake of the placental tissue remained unchanged. The RNA content of the placenta decreased notably after fetal death. It is supposed that the role of gram-negative bacteria in pathology of pregnancy is brought about by the inhibition of placental metabolism by the action of their endotoxin.
AB - An inhibition of aerobic glycolysis in the placental tissue of rat was demonstrable one hour after administration of endotoxin and was still present after 48 hours. However, oxygen uptake of the placental tissue remained unchanged. The RNA content of the placenta decreased notably after fetal death. It is supposed that the role of gram-negative bacteria in pathology of pregnancy is brought about by the inhibition of placental metabolism by the action of their endotoxin.
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UR - http://www.scopus.com/inward/citedby.url?scp=0014205881&partnerID=8YFLogxK
M3 - Article
C2 - 4951897
AN - SCOPUS:0014205881
VL - 98
SP - 1129
EP - 1134
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 8
ER -