An inhibition of aerobic glycolysis in the placental tissue of rat was demonstrable one hour after administration of endotoxin and was still present after 48 hours. However, oxygen uptake of the placental tissue remained unchanged. The RNA content of the placenta decreased notably after fetal death. It is supposed that the role of gram-negative bacteria in pathology of pregnancy is brought about by the inhibition of placental metabolism by the action of their endotoxin.
|Number of pages||6|
|Journal||American Journal of Obstetrics and Gynecology|
|Publication status||Published - aug. 15 1967|
ASJC Scopus subject areas
- Obstetrics and Gynaecology