Korábban és hatékonyabban: A mély agyi stimuláció szerepe a munkaképesség megorzésében

Gabriella Deli, István Bálás, Sámuel Komoly, Tamás Dóczi, József Janszky, Zsuzsanna Aschermann, Ferenc Nagy, Edit Bosnyák, Norbert Kovács

Research output: Article

Abstract

Background: The recently published "EarlyStim" study demonstrated that deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD) with early fluctuations is superior to the optimal pharmacological treatment in improving the quality of life and motor symptoms, and preserving sociocultural position. Our retrospective investigation aimed to evaluate if DBS therapy was able to preserve the working capabilities of our patients. Methods: We reviewed the data of 39 young (<60 yearsold) PD patients who underwent subthalamic DBS implantation at University of Pécs and had at least two years followup. Patients were categorized into two groups based on their working capabilities: Patients with active job ("Job+" group, n=15) and retired patients (without active job, "Job-" group, n=24). Severity of motor symptoms (UPDRS part 3), quality of life (EQ-5D) and presence of active job were evaluated one and two years after the operation. Results: As far as the severity of motor symptoms were concerned, similar (approximately 50%) improvement was achieved in both groups. However, the postoperative quality of life was significantly better in the Job-t-group. Majority (12/15, 80%) of Job+ group members were able to preserve their job two years after the operation. However, only a minimal portion (1/24, 4.2%) of the Job-group members was able to return to the world of active employees (p<0.01, McNemar test). Conclusion: Although our retrospective study has several limitations, our results fit well with the conclusions of "EarlyStim" study. Both of them suggest that with optimal timing of DBS implantation we may preserve the working capabilities of our patients.

Translated title of the contributionEarlier and more efficiently: The role of deep brain stimulation for Parkinson's disease preserving the working capabilities
Original languageHungarian
Pages (from-to)384-390
Number of pages7
JournalIdeggyogyaszati szemle
Volume68
Issue number11-12
DOIs
Publication statusPublished - nov. 30 2015

Keywords

  • Deep brain stimulation
  • Parkinson's disease
  • Quality of life
  • Working ability

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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