Donation After Cardiac Death, a Possibility to Expand the Donor Pool

Review and the Hungarian Experience

Áron K. Ghimessy, Attila Farkas, Balázs Gieszer, Péter Radeczky, Kristóf Csende, László Mészáros, Klára Török, Levente Fazekas, László Agócs, Ákos Kocsis, Tibor Bartók, Tamás Dancs, Krisztina Kormosoi Tóth, Nóra Schönauer, Ildikó Madurka, Jenő Elek, B. Döme, Férenc Rényi-Vámos, György Lang, Shahrokh Taghavi & 3 others Konrad Hötzenecker, Walter Klepetko, Levente Bogyó

Research output: Article

Abstract

Introduction: Lung transplantation is the only successful treatment option for patients experiencing end-stage lung disease. Results have improved significantly in the last decade; however, the number one limiting factor is still the shortage of donor lungs. Due to the discrepancy between available donor lungs and patients awaiting lung transplantation, many centers have reintroduced donation after cardiac death (DCD). According to their results, DCD and donation after brain death (DBD) are comparable in terms of survival and graft function. Currently in Hungary, donation is only allowed from DBD donors; however, due to the Eurotransplant agreement, non-heart-beating donation (NHBD) organs can be transplanted into Hungarian patients, and in some cases Hungarian transplant teams can also take part in NHBDs within the Eurotransplant region. The Hungarian experience. A Hungarian patient received a lung from a 15-year-old uncontrolled DCD in Vienna. The donor was reanimated for 54 minutes and after lung procurement the lungs were put on ex vivo lung perfusion and later successfully implanted into the Hungarian recipient. The recovery was very successful and the patient is still alive. The Hungarian Lung Transplantation Team was involved in a controlled Maastricht III donation in 2017. A 49-year-old female donor was reported from Ghent, Belgium. A multiorgan donation was carried out with 15 minutes of warm ischemic time in the case of the lungs. Conclusion: DCD is an effective, safe, and available method to increase the donor pool. In the case of controlled donations, the necessary protocols have already been prepared. Although DBD is working very successfully in Hungary, infrastructural developments, education of professionals, and social preparations are all needed to implement a DCD protocol in Hungary.

Original languageEnglish
Pages (from-to)1276-1280
Number of pages5
JournalTransplantation Proceedings
Volume51
Issue number4
DOIs
Publication statusPublished - máj. 1 2019

Fingerprint

Tissue Donors
Lung
Brain Death
Lung Transplantation
Hungary
Warm Ischemia
Professional Education
Tissue and Organ Procurement
Belgium
Graft Survival
Lung Diseases
Perfusion
Transplants
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Ghimessy, Á. K., Farkas, A., Gieszer, B., Radeczky, P., Csende, K., Mészáros, L., ... Bogyó, L. (2019). Donation After Cardiac Death, a Possibility to Expand the Donor Pool: Review and the Hungarian Experience. Transplantation Proceedings, 51(4), 1276-1280. https://doi.org/10.1016/j.transproceed.2019.04.003

Donation After Cardiac Death, a Possibility to Expand the Donor Pool : Review and the Hungarian Experience. / Ghimessy, Áron K.; Farkas, Attila; Gieszer, Balázs; Radeczky, Péter; Csende, Kristóf; Mészáros, László; Török, Klára; Fazekas, Levente; Agócs, László; Kocsis, Ákos; Bartók, Tibor; Dancs, Tamás; Tóth, Krisztina Kormosoi; Schönauer, Nóra; Madurka, Ildikó; Elek, Jenő; Döme, B.; Rényi-Vámos, Férenc; Lang, György; Taghavi, Shahrokh; Hötzenecker, Konrad; Klepetko, Walter; Bogyó, Levente.

In: Transplantation Proceedings, Vol. 51, No. 4, 01.05.2019, p. 1276-1280.

Research output: Article

Ghimessy, ÁK, Farkas, A, Gieszer, B, Radeczky, P, Csende, K, Mészáros, L, Török, K, Fazekas, L, Agócs, L, Kocsis, Á, Bartók, T, Dancs, T, Tóth, KK, Schönauer, N, Madurka, I, Elek, J, Döme, B, Rényi-Vámos, F, Lang, G, Taghavi, S, Hötzenecker, K, Klepetko, W & Bogyó, L 2019, 'Donation After Cardiac Death, a Possibility to Expand the Donor Pool: Review and the Hungarian Experience', Transplantation Proceedings, vol. 51, no. 4, pp. 1276-1280. https://doi.org/10.1016/j.transproceed.2019.04.003
Ghimessy, Áron K. ; Farkas, Attila ; Gieszer, Balázs ; Radeczky, Péter ; Csende, Kristóf ; Mészáros, László ; Török, Klára ; Fazekas, Levente ; Agócs, László ; Kocsis, Ákos ; Bartók, Tibor ; Dancs, Tamás ; Tóth, Krisztina Kormosoi ; Schönauer, Nóra ; Madurka, Ildikó ; Elek, Jenő ; Döme, B. ; Rényi-Vámos, Férenc ; Lang, György ; Taghavi, Shahrokh ; Hötzenecker, Konrad ; Klepetko, Walter ; Bogyó, Levente. / Donation After Cardiac Death, a Possibility to Expand the Donor Pool : Review and the Hungarian Experience. In: Transplantation Proceedings. 2019 ; Vol. 51, No. 4. pp. 1276-1280.
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T2 - Review and the Hungarian Experience

AU - Ghimessy, Áron K.

AU - Farkas, Attila

AU - Gieszer, Balázs

AU - Radeczky, Péter

AU - Csende, Kristóf

AU - Mészáros, László

AU - Török, Klára

AU - Fazekas, Levente

AU - Agócs, László

AU - Kocsis, Ákos

AU - Bartók, Tibor

AU - Dancs, Tamás

AU - Tóth, Krisztina Kormosoi

AU - Schönauer, Nóra

AU - Madurka, Ildikó

AU - Elek, Jenő

AU - Döme, B.

AU - Rényi-Vámos, Férenc

AU - Lang, György

AU - Taghavi, Shahrokh

AU - Hötzenecker, Konrad

AU - Klepetko, Walter

AU - Bogyó, Levente

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