Does hospitalization predict the disease course in ulcerative colitis? Prevalence and predictors of hospitalization and rehospitalization in ulcerative colitis in a population-based inception cohort (2000-2012)

Petra A. Golovics, L. Lakatos, Michael D. Mandel, Barbara D. Lovasz, Zsuzsanna Vegh, Zsuzsanna Kurti, Istvan Szita, Lajos S. Kiss, Mihaly Balogh, T. Pandúr, P. Lakatos

Research output: Article

5 Citations (Scopus)

Abstract

Background & Aims: Limited data are available on the hospitalization rates in population-based studies. Since this is a very important outcome measure, the aim of this study was to analyze prospectively if early hospitalization is associated with the later disease course as well as to determine the prevalence and predictors of hospitalization and re-hospitalization in the population-based ulcerative colitis (UC) inception cohort in the Veszprem province database between 2000 and 2012. Methods: Data of 347 incident UC patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed (M/F: 200/147, median age at diagnosis: 36, IQR: 26-50 years, follow-up duration: 7, IQR 4-10 years). Both in- and outpatient records were collected and comprehensively reviewed. Results: Probabilities of first UC-related hospitalization were 28.6%, 53.7% and 66.2% and of first rehospitalization were 23.7%, 55.8% and 74.6% after 1-, 5- and 10- years of follow-up, respectively. Main UC-related causes for first hospitalization were diagnostic procedures (26.7%), disease activity (22.4%) or UC-related surgery (4.8%), but a significant percentage was unrelated to IBD (44.8%). In Kaplan-Meier and Cox-regression analysis disease extent at diagnosis (HR extensive: 1.79, p=0.02) or at last follow-up (HR: 1.56, p=0.001), need for steroids (HR: 1.98, p

Original languageEnglish
Pages (from-to)287-292
Number of pages6
JournalJournal of gastrointestinal and liver diseases : JGLD
Volume24
Issue number3
DOIs
Publication statusPublished - szept. 1 2015

Fingerprint

Ulcerative Colitis
Hospitalization
Population
Inpatients
Outpatients
Steroids
Regression Analysis
Outcome Assessment (Health Care)
Databases

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Does hospitalization predict the disease course in ulcerative colitis? Prevalence and predictors of hospitalization and rehospitalization in ulcerative colitis in a population-based inception cohort (2000-2012). / Golovics, Petra A.; Lakatos, L.; Mandel, Michael D.; Lovasz, Barbara D.; Vegh, Zsuzsanna; Kurti, Zsuzsanna; Szita, Istvan; Kiss, Lajos S.; Balogh, Mihaly; Pandúr, T.; Lakatos, P.

In: Journal of gastrointestinal and liver diseases : JGLD, Vol. 24, No. 3, 01.09.2015, p. 287-292.

Research output: Article

@article{5483f0ba800b4c988de45499bfdd6cdd,
title = "Does hospitalization predict the disease course in ulcerative colitis? Prevalence and predictors of hospitalization and rehospitalization in ulcerative colitis in a population-based inception cohort (2000-2012)",
abstract = "Background & Aims: Limited data are available on the hospitalization rates in population-based studies. Since this is a very important outcome measure, the aim of this study was to analyze prospectively if early hospitalization is associated with the later disease course as well as to determine the prevalence and predictors of hospitalization and re-hospitalization in the population-based ulcerative colitis (UC) inception cohort in the Veszprem province database between 2000 and 2012. Methods: Data of 347 incident UC patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed (M/F: 200/147, median age at diagnosis: 36, IQR: 26-50 years, follow-up duration: 7, IQR 4-10 years). Both in- and outpatient records were collected and comprehensively reviewed. Results: Probabilities of first UC-related hospitalization were 28.6{\%}, 53.7{\%} and 66.2{\%} and of first rehospitalization were 23.7{\%}, 55.8{\%} and 74.6{\%} after 1-, 5- and 10- years of follow-up, respectively. Main UC-related causes for first hospitalization were diagnostic procedures (26.7{\%}), disease activity (22.4{\%}) or UC-related surgery (4.8{\%}), but a significant percentage was unrelated to IBD (44.8{\%}). In Kaplan-Meier and Cox-regression analysis disease extent at diagnosis (HR extensive: 1.79, p=0.02) or at last follow-up (HR: 1.56, p=0.001), need for steroids (HR: 1.98, p",
keywords = "Disease course, Hospitalization, Population-based, Predictors, Ulcerative colitis",
author = "Golovics, {Petra A.} and L. Lakatos and Mandel, {Michael D.} and Lovasz, {Barbara D.} and Zsuzsanna Vegh and Zsuzsanna Kurti and Istvan Szita and Kiss, {Lajos S.} and Mihaly Balogh and T. Pand{\'u}r and P. Lakatos",
year = "2015",
month = "9",
day = "1",
doi = "10.15403/jgld.2014.1121.243.pag",
language = "English",
volume = "24",
pages = "287--292",
journal = "Journal of gastrointestinal and liver diseases : JGLD",
issn = "1841-8724",
publisher = "Romanian Society of Gastroenterology",
number = "3",

}

TY - JOUR

T1 - Does hospitalization predict the disease course in ulcerative colitis? Prevalence and predictors of hospitalization and rehospitalization in ulcerative colitis in a population-based inception cohort (2000-2012)

AU - Golovics, Petra A.

AU - Lakatos, L.

AU - Mandel, Michael D.

AU - Lovasz, Barbara D.

AU - Vegh, Zsuzsanna

AU - Kurti, Zsuzsanna

AU - Szita, Istvan

AU - Kiss, Lajos S.

AU - Balogh, Mihaly

AU - Pandúr, T.

AU - Lakatos, P.

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Background & Aims: Limited data are available on the hospitalization rates in population-based studies. Since this is a very important outcome measure, the aim of this study was to analyze prospectively if early hospitalization is associated with the later disease course as well as to determine the prevalence and predictors of hospitalization and re-hospitalization in the population-based ulcerative colitis (UC) inception cohort in the Veszprem province database between 2000 and 2012. Methods: Data of 347 incident UC patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed (M/F: 200/147, median age at diagnosis: 36, IQR: 26-50 years, follow-up duration: 7, IQR 4-10 years). Both in- and outpatient records were collected and comprehensively reviewed. Results: Probabilities of first UC-related hospitalization were 28.6%, 53.7% and 66.2% and of first rehospitalization were 23.7%, 55.8% and 74.6% after 1-, 5- and 10- years of follow-up, respectively. Main UC-related causes for first hospitalization were diagnostic procedures (26.7%), disease activity (22.4%) or UC-related surgery (4.8%), but a significant percentage was unrelated to IBD (44.8%). In Kaplan-Meier and Cox-regression analysis disease extent at diagnosis (HR extensive: 1.79, p=0.02) or at last follow-up (HR: 1.56, p=0.001), need for steroids (HR: 1.98, p

AB - Background & Aims: Limited data are available on the hospitalization rates in population-based studies. Since this is a very important outcome measure, the aim of this study was to analyze prospectively if early hospitalization is associated with the later disease course as well as to determine the prevalence and predictors of hospitalization and re-hospitalization in the population-based ulcerative colitis (UC) inception cohort in the Veszprem province database between 2000 and 2012. Methods: Data of 347 incident UC patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed (M/F: 200/147, median age at diagnosis: 36, IQR: 26-50 years, follow-up duration: 7, IQR 4-10 years). Both in- and outpatient records were collected and comprehensively reviewed. Results: Probabilities of first UC-related hospitalization were 28.6%, 53.7% and 66.2% and of first rehospitalization were 23.7%, 55.8% and 74.6% after 1-, 5- and 10- years of follow-up, respectively. Main UC-related causes for first hospitalization were diagnostic procedures (26.7%), disease activity (22.4%) or UC-related surgery (4.8%), but a significant percentage was unrelated to IBD (44.8%). In Kaplan-Meier and Cox-regression analysis disease extent at diagnosis (HR extensive: 1.79, p=0.02) or at last follow-up (HR: 1.56, p=0.001), need for steroids (HR: 1.98, p

KW - Disease course

KW - Hospitalization

KW - Population-based

KW - Predictors

KW - Ulcerative colitis

UR - http://www.scopus.com/inward/record.url?scp=84941065575&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941065575&partnerID=8YFLogxK

U2 - 10.15403/jgld.2014.1121.243.pag

DO - 10.15403/jgld.2014.1121.243.pag

M3 - Article

VL - 24

SP - 287

EP - 292

JO - Journal of gastrointestinal and liver diseases : JGLD

JF - Journal of gastrointestinal and liver diseases : JGLD

SN - 1841-8724

IS - 3

ER -