Divergent microsatellite evolution in the human and chimpanzee lineages

Zoltán Gáspári, Csaba Ortutay, Gábor Tóth

Research output: Article

10 Citations (Scopus)

Abstract

Comparison of the complete human genome sequence to one of its closest relatives, the chimpanzee genome, provides a unique opportunity for exploring recent evolutionary events affecting the microsatellites in these species. A simple assumption on microsatellite distribution is that the total length of perfect repeats is constant compared to that of imperfect ones regardless of the repeat sequence. In this paper, we show that this is valid for most of the chimpanzee genome but not for a number of human chromosomes. Our results suggest accelerated evolution of microsatellites in the human genome relative to the chimpanzee lineage.

Original languageEnglish
Pages (from-to)2523-2526
Number of pages4
JournalFEBS letters
Volume581
Issue number13
DOIs
Publication statusPublished - máj. 29 2007

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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