Dimethyldioxirane epoxidation of aurones and isoflavones

W. Adam, L. Hadjiarapoglou, A. Lévai

Research output: Article

27 Citations (Scopus)

Abstract

The synthesis of the corresponding epoxides 2 and 4 by epoxidation of aurones (2-benzylidenebenzofuran-3(2H)-ones, 1) and isoflavones (3-aryl-4H-1-benzopyran-4-ones, 3) with dimethyldioxirane at subambient temperatures is reported. These acid- and base-sensitive epoxides, which have been previously difficult to prepare, were isolated in excellent yields and were completely characterized by spectral and microanalytical data. The now readily available aurone and/or isoflavone oxides may serve as convenient precursors to flavonoid-type natural products.

Original languageEnglish
Pages (from-to)436-438
Number of pages3
JournalSynthesis
Issue number5
Publication statusPublished - 1992

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Flavonoids
Isoflavones
Epoxidation
Epoxy Compounds
Oxides
Acids
Biological Products
Temperature
dimethyldioxirane
aurone

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Adam, W., Hadjiarapoglou, L., & Lévai, A. (1992). Dimethyldioxirane epoxidation of aurones and isoflavones. Synthesis, (5), 436-438.

Dimethyldioxirane epoxidation of aurones and isoflavones. / Adam, W.; Hadjiarapoglou, L.; Lévai, A.

In: Synthesis, No. 5, 1992, p. 436-438.

Research output: Article

Adam, W, Hadjiarapoglou, L & Lévai, A 1992, 'Dimethyldioxirane epoxidation of aurones and isoflavones', Synthesis, no. 5, pp. 436-438.
Adam, W. ; Hadjiarapoglou, L. ; Lévai, A. / Dimethyldioxirane epoxidation of aurones and isoflavones. In: Synthesis. 1992 ; No. 5. pp. 436-438.
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