Differentiation of Human Embryonal Carcinoma Cells Induces Human Immunodeficiency Virus Permissiveness Which Is Stimulated by Human Cytomegalovirus Coinfection

Gabor Hirka, Kesh Prakash, Hisashi Kawashima, Stanley A. Plotkin, Peter W. Andrews, E. Gönczöl

Research output: Article

26 Citations (Scopus)

Abstract

Human immunodeficiency virus (HIV) replicates in differentiated but not undifferentiated NTERA-2 human embryonal carcinoma cells; neither cell type expresses CD4. Susceptibility of the differentiated cells is enhanced by coinfection with cytomegalovirus. HIV infection induces lactoseries glycolipids, suggesting a mechanism whereby HIV might interfere with normal embryogenesis.

Original languageEnglish
Pages (from-to)2732-2735
Number of pages4
JournalJournal of Virology
Volume65
Issue number5
Publication statusPublished - máj. 1991

Fingerprint

Permissiveness
Human herpesvirus 5
Embryonal Carcinoma Stem Cells
Human immunodeficiency virus
Cytomegalovirus
Coinfection
mixed infection
carcinoma
HIV
glycolipids
Glycolipids
HIV infections
Virus Diseases
cells
Embryonic Development
embryogenesis

ASJC Scopus subject areas

  • Immunology

Cite this

Differentiation of Human Embryonal Carcinoma Cells Induces Human Immunodeficiency Virus Permissiveness Which Is Stimulated by Human Cytomegalovirus Coinfection. / Hirka, Gabor; Prakash, Kesh; Kawashima, Hisashi; Plotkin, Stanley A.; Andrews, Peter W.; Gönczöl, E.

In: Journal of Virology, Vol. 65, No. 5, 05.1991, p. 2732-2735.

Research output: Article

Hirka, Gabor ; Prakash, Kesh ; Kawashima, Hisashi ; Plotkin, Stanley A. ; Andrews, Peter W. ; Gönczöl, E. / Differentiation of Human Embryonal Carcinoma Cells Induces Human Immunodeficiency Virus Permissiveness Which Is Stimulated by Human Cytomegalovirus Coinfection. In: Journal of Virology. 1991 ; Vol. 65, No. 5. pp. 2732-2735.
@article{f5ef58e69a9b4537b38d36b82728369f,
title = "Differentiation of Human Embryonal Carcinoma Cells Induces Human Immunodeficiency Virus Permissiveness Which Is Stimulated by Human Cytomegalovirus Coinfection",
abstract = "Human immunodeficiency virus (HIV) replicates in differentiated but not undifferentiated NTERA-2 human embryonal carcinoma cells; neither cell type expresses CD4. Susceptibility of the differentiated cells is enhanced by coinfection with cytomegalovirus. HIV infection induces lactoseries glycolipids, suggesting a mechanism whereby HIV might interfere with normal embryogenesis.",
author = "Gabor Hirka and Kesh Prakash and Hisashi Kawashima and Plotkin, {Stanley A.} and Andrews, {Peter W.} and E. G{\"o}ncz{\"o}l",
year = "1991",
month = "5",
language = "English",
volume = "65",
pages = "2732--2735",
journal = "Journal of Virology",
issn = "0022-538X",
publisher = "American Society for Microbiology",
number = "5",

}

TY - JOUR

T1 - Differentiation of Human Embryonal Carcinoma Cells Induces Human Immunodeficiency Virus Permissiveness Which Is Stimulated by Human Cytomegalovirus Coinfection

AU - Hirka, Gabor

AU - Prakash, Kesh

AU - Kawashima, Hisashi

AU - Plotkin, Stanley A.

AU - Andrews, Peter W.

AU - Gönczöl, E.

PY - 1991/5

Y1 - 1991/5

N2 - Human immunodeficiency virus (HIV) replicates in differentiated but not undifferentiated NTERA-2 human embryonal carcinoma cells; neither cell type expresses CD4. Susceptibility of the differentiated cells is enhanced by coinfection with cytomegalovirus. HIV infection induces lactoseries glycolipids, suggesting a mechanism whereby HIV might interfere with normal embryogenesis.

AB - Human immunodeficiency virus (HIV) replicates in differentiated but not undifferentiated NTERA-2 human embryonal carcinoma cells; neither cell type expresses CD4. Susceptibility of the differentiated cells is enhanced by coinfection with cytomegalovirus. HIV infection induces lactoseries glycolipids, suggesting a mechanism whereby HIV might interfere with normal embryogenesis.

UR - http://www.scopus.com/inward/record.url?scp=0025834293&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025834293&partnerID=8YFLogxK

M3 - Article

VL - 65

SP - 2732

EP - 2735

JO - Journal of Virology

JF - Journal of Virology

SN - 0022-538X

IS - 5

ER -