Differential outcome of the IDEFICS intervention in overweight versus non-overweight children: Did we achieve 'primary' or 'secondary' prevention?

on behalf of the IDEFICS consortium

Research output: Article

11 Citations (Scopus)

Abstract

Background: The aim of this study was to explore whether the IDEFICS intervention had a differential effect on 11,041 children's weight trajectories depending on their baseline body mass index status. Methods: Two subgroups of children are considered in the present analysis: those who were overweight or obese prior to the intervention and those who were neither overweight nor obese. Results: Among children in all eight countries who did not have prevalent overweight or obesity (OWOB) at baseline, 2years later, there was no significant difference between intervention and control groups in risk of having developed OWOB. However, we observed a strong regional heterogeneity, which could be attributed to the presence of one distinctly outlying country, Belgium, where the intervention group had increased risk for becoming overweight. In contrast, among the sample of children with prevalent OWOB at baseline, we observed a significantly greater probability of normalized weight status after 2years. In other words, a protective effect against persistent OWOB was observed in children in intervention regions compared with controls, which corresponded to an adjusted odds ratio of 0.76 (95% confidence interval: 0.58, 0.98). Discussion: This analysis thus provided evidence of a differential effect of the IDEFICS intervention, in which children with overweight may have benefited without having been specifically targeted. However, no overall primary preventive effect could be observed in children without initial overweight or obesity.

Original languageEnglish
Pages (from-to)119-126
Number of pages8
JournalObesity Reviews
Volume16
DOIs
Publication statusPublished - dec. 1 2015

Fingerprint

Secondary Prevention
Obesity
Weights and Measures
Belgium
Body Mass Index
Odds Ratio
Confidence Intervals
Control Groups

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Endocrinology, Diabetes and Metabolism

Cite this

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title = "Differential outcome of the IDEFICS intervention in overweight versus non-overweight children: Did we achieve 'primary' or 'secondary' prevention?",
abstract = "Background: The aim of this study was to explore whether the IDEFICS intervention had a differential effect on 11,041 children's weight trajectories depending on their baseline body mass index status. Methods: Two subgroups of children are considered in the present analysis: those who were overweight or obese prior to the intervention and those who were neither overweight nor obese. Results: Among children in all eight countries who did not have prevalent overweight or obesity (OWOB) at baseline, 2years later, there was no significant difference between intervention and control groups in risk of having developed OWOB. However, we observed a strong regional heterogeneity, which could be attributed to the presence of one distinctly outlying country, Belgium, where the intervention group had increased risk for becoming overweight. In contrast, among the sample of children with prevalent OWOB at baseline, we observed a significantly greater probability of normalized weight status after 2years. In other words, a protective effect against persistent OWOB was observed in children in intervention regions compared with controls, which corresponded to an adjusted odds ratio of 0.76 (95{\%} confidence interval: 0.58, 0.98). Discussion: This analysis thus provided evidence of a differential effect of the IDEFICS intervention, in which children with overweight may have benefited without having been specifically targeted. However, no overall primary preventive effect could be observed in children without initial overweight or obesity.",
keywords = "Childhood obesity, Intervention, Primary prevention, Secondary prevention",
author = "{on behalf of the IDEFICS consortium} and L. Lissner and {de Bourdeaudhuij}, I. and K. Konstabel and S. M{\aa}rild and K. Mehlig and D. Moln{\'a}r and Moreno, {L. A.} and I. Pigeot and A. Siani and M. Tornaritis and G. Williams and {de Henauw}, S.",
year = "2015",
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T1 - Differential outcome of the IDEFICS intervention in overweight versus non-overweight children

T2 - Did we achieve 'primary' or 'secondary' prevention?

AU - on behalf of the IDEFICS consortium

AU - Lissner, L.

AU - de Bourdeaudhuij, I.

AU - Konstabel, K.

AU - Mårild, S.

AU - Mehlig, K.

AU - Molnár, D.

AU - Moreno, L. A.

AU - Pigeot, I.

AU - Siani, A.

AU - Tornaritis, M.

AU - Williams, G.

AU - de Henauw, S.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Background: The aim of this study was to explore whether the IDEFICS intervention had a differential effect on 11,041 children's weight trajectories depending on their baseline body mass index status. Methods: Two subgroups of children are considered in the present analysis: those who were overweight or obese prior to the intervention and those who were neither overweight nor obese. Results: Among children in all eight countries who did not have prevalent overweight or obesity (OWOB) at baseline, 2years later, there was no significant difference between intervention and control groups in risk of having developed OWOB. However, we observed a strong regional heterogeneity, which could be attributed to the presence of one distinctly outlying country, Belgium, where the intervention group had increased risk for becoming overweight. In contrast, among the sample of children with prevalent OWOB at baseline, we observed a significantly greater probability of normalized weight status after 2years. In other words, a protective effect against persistent OWOB was observed in children in intervention regions compared with controls, which corresponded to an adjusted odds ratio of 0.76 (95% confidence interval: 0.58, 0.98). Discussion: This analysis thus provided evidence of a differential effect of the IDEFICS intervention, in which children with overweight may have benefited without having been specifically targeted. However, no overall primary preventive effect could be observed in children without initial overweight or obesity.

AB - Background: The aim of this study was to explore whether the IDEFICS intervention had a differential effect on 11,041 children's weight trajectories depending on their baseline body mass index status. Methods: Two subgroups of children are considered in the present analysis: those who were overweight or obese prior to the intervention and those who were neither overweight nor obese. Results: Among children in all eight countries who did not have prevalent overweight or obesity (OWOB) at baseline, 2years later, there was no significant difference between intervention and control groups in risk of having developed OWOB. However, we observed a strong regional heterogeneity, which could be attributed to the presence of one distinctly outlying country, Belgium, where the intervention group had increased risk for becoming overweight. In contrast, among the sample of children with prevalent OWOB at baseline, we observed a significantly greater probability of normalized weight status after 2years. In other words, a protective effect against persistent OWOB was observed in children in intervention regions compared with controls, which corresponded to an adjusted odds ratio of 0.76 (95% confidence interval: 0.58, 0.98). Discussion: This analysis thus provided evidence of a differential effect of the IDEFICS intervention, in which children with overweight may have benefited without having been specifically targeted. However, no overall primary preventive effect could be observed in children without initial overweight or obesity.

KW - Childhood obesity

KW - Intervention

KW - Primary prevention

KW - Secondary prevention

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