Dicipivirus (family Picornaviridae) in wild Northern white-breasted hedgehog (Erinaceus roumanicus)

G. Reuter, Ákos Boros, G. Földvári, Sándor Szekeres, Róbert Mátics, Beatrix Kapusinszky, Eric Delwart, P. Pankovics

Research output: Article

4 Citations (Scopus)

Abstract

Using random amplification and high-throughput sequencing technology a novel picornavirus with dicistronic genome organization and genetically related to canine picodicistrovirus (genus Dicipivirus, family Picornaviridae) was identified and characterized in Northern white-breasted hedgehogs. Hedgehog dicipivirus (hedgehog/H14/2015/HUN, MF188967) was detected in 15 (75%) of 20 faecal specimens by RT-PCR with high viral loads (up to 8.2x108 genomic copies/ml faeces). Hedgehog dicipivirus RNA was also identified in blood, ear skin, abdominal muscle and liver tissues. While the general dicistronic genome organization of hedgehog/H14/2015/HUN is similar to canine picodicistrovirus (5’UTR-P1-IGR-P2/P3-3UTR) there are some unique genome characteristics within the untranslated regions, especially in the functional IRES elements. This study reports the putative second member of the genus Dicipivirus, in a novel host species.

Original languageEnglish
Pages (from-to)175-181
Number of pages7
JournalArchives of Virology
Volume163
Issue number1
DOIs
Publication statusPublished - jan. 1 2018

Fingerprint

Picornaviridae
Genome
Canidae
Untranslated Regions
Abdominal Muscles
Viral Load
Feces
Ear
RNA
Technology
Muscles
Polymerase Chain Reaction
Skin
Liver

ASJC Scopus subject areas

  • Virology

Cite this

Dicipivirus (family Picornaviridae) in wild Northern white-breasted hedgehog (Erinaceus roumanicus). / Reuter, G.; Boros, Ákos; Földvári, G.; Szekeres, Sándor; Mátics, Róbert; Kapusinszky, Beatrix; Delwart, Eric; Pankovics, P.

In: Archives of Virology, Vol. 163, No. 1, 01.01.2018, p. 175-181.

Research output: Article

Reuter, G. ; Boros, Ákos ; Földvári, G. ; Szekeres, Sándor ; Mátics, Róbert ; Kapusinszky, Beatrix ; Delwart, Eric ; Pankovics, P. / Dicipivirus (family Picornaviridae) in wild Northern white-breasted hedgehog (Erinaceus roumanicus). In: Archives of Virology. 2018 ; Vol. 163, No. 1. pp. 175-181.
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