Devic-szindróma - Esetismertetés, valamint a diagnosztika és a kezelés aktuális elvei

Anna Iljlcsov, Péter Barsi, György Várallyay, Erika Tátrai, Gábor Márk Somfai, Dániel Bereczki, Gábor Rudas, Magdolna Simó

Research output: Article

2 Citations (Scopus)

Abstract

Neuromyelitis optica (NMO, Devic-syndrome) is a rare, relapsing autoimmun disease of the central nervous system, which is distinguished from other demyelinating disorders by a recently identified, specific autoantibody. By demonstrating the anti-aquaporin-4 IgG in the serum, a heterogenous group of syndromes can be defined, called NMO-spectrum. In the future, optical coherence tomography may support this diagnosis besides the clinical features, imaging examinations and presence of serum antibody. Early recognition and treatment can improve clinical outcome even in serious condition. Long-term immunosuppressive therapy is advised to prevent further relapses and to stabilize or improve clinical status. Hereby, we report a case of a 51-year-old woman, under treatment for 1.5 years. We summarize the up-to-date knowledge about the pathomechanism, diagnostic strategy and therapy of neuromyelitis optica. We review recent findings and the diagnostic value of a new, non-invasive ophtalmological examination, the optical coherence tomography. According to the first results, this method may be helpful in the early differential diagnosis of optic neuritis.

Translated title of the contributionDevic syndrome - Case report, diagnostic and therapeutic principles
Original languageHungarian
Pages (from-to)320-326
Number of pages7
JournalIdeggyogyaszati szemle
Volume63
Issue number9-10
Publication statusPublished - szept. 30 2010

Keywords

  • Devic-syndrome
  • Diagnostic criteria
  • Neuromyelitis optica
  • Optical coherence tomography (OCT)

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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