Detection of volatile compounds correlated to human diseases through breath analysis with chemical sensors

Maximilian Fleischer, Elfriede Simon, Eva Rumpel, Heiko Ulmer, Mika Harbeck, Michael Wandel, Christopher Fietzek, Udo Weimar, Hans Meixner

Research output: Conference article

133 Citations (Scopus)


The analysis of volatile compounds in the breath of humans was investigated by the application of different sensor principles. The detection of nitrogen oxide, an asthma marker, in breath at the low ppb-level (2-100ppb) can be carried out by work function measurements. By the use of Cu-phthalocyanine dye as gas sensitive layer a calculated detection limit of 1.3ppb is attainable. The low cross sensitivities to water and changes in the oxygen concentration are of great advantage for the use in breath analysis. With quartz microbalance (QMB) measurements acetone concentrations, a marker for diabetes, can be determined in the presence of ethanol and water vapor. The comparison of both sensor principles showed no correlation, hence, the combination can improve cross sensitivity and sensor selectivity.

Original languageEnglish
Pages (from-to)245-249
Number of pages5
JournalSensors and Actuators, B: Chemical
Issue number1-3
Publication statusPublished - márc. 15 2002
EventSelected papers from Transduckers '01 Eurosensors XV (Transduckers 2001) - Munich, Germany
Duration: jún. 10 2001jún. 14 2001


ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

Cite this