Design, synthesis and potential use of 3,9‐substituted xanthene handles for Solid Phase Peptide Synthesis

Csaba Somlai, Levente Nyerges, Botond Penke, Péter Hegyes, Wolfgang Voelter

Research output: Article

5 Citations (Scopus)

Abstract

Theoretical calculations on different xanthene derivatives and related structures were performed and as a result conclusions could be drawn for the acid‐lability of substituted xanthenes. (9‐Hydroxyxanthene‐3‐oxy)acetic‐ and valeric acid (6a and 6b) were selected, synthesized in a six‐step route, and 6b was tested for its applicabiliy as a handle for solid phase synthesis of peptides.

Original languageEnglish
Pages (from-to)429-433
Number of pages5
JournalJournal für Praktische Chemie/Chemiker‐Zeitung
Volume336
Issue number5
DOIs
Publication statusPublished - 1994

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ASJC Scopus subject areas

  • Chemistry(all)

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