Current approaches to use cyclodextrins and mucoadhesive polymers in ocular drug delivery-a mini-review

Tivadar Bíró, Zoltán Aigner

Research output: Article

2 Citations (Scopus)

Abstract

Ocular drug delivery provides a challenging opportunity to develop optimal formulations with proper therapeutic effects and acceptable patient compliance because there are many restricting factors involved, such as complex anatomical structures, defensive mechanisms, rapid drainage, and applicability issues. Fortunately, recent advances in the field mean that these problems can be overcome through the formulation of innovative ophthalmic products. Through the addition of solubility enhancer cyclodextrin derivatives and mucoadhesive polymers, the permeability of active ingredients is improved, and retention time is increased in the ocular surface. Therefore, preferable efficacy and bioavailability can be achieved. In this short review, the authors describe the theoretical background, technological possibilities, and the current approaches in the field of ophthalmology.

Original languageEnglish
Article number15
JournalScientia Pharmaceutica
Volume87
Issue number3
DOIs
Publication statusPublished - szept. 2019

ASJC Scopus subject areas

  • Pharmaceutical Science

Fingerprint Dive into the research topics of 'Current approaches to use cyclodextrins and mucoadhesive polymers in ocular drug delivery-a mini-review'. Together they form a unique fingerprint.

  • Cite this