Covalent grafting of Cu(II)-histidine complexes on polystyrene resin studied by Photoacoustic Infrared Spectroscopy

O. Berkesi, Tímea Szabó, Barbara Korbély, K. Hernádi, I. Pálinkó

Research output: Conference contribution

Abstract

In order to mimic copper-containing enzymes, Cu(II)-histidine complexes were grafted onto chloropropylated polystyrene resin. The Cu(II)-histidine complexes and the mobile polymer were thought to resemble the active centre and the proteomic skeleton of the enzymes, respectively. The resulting heterogenised complexes were expected to be nearly so active, selective and more durable catalysts that are easier to recycle than their homogeneous counterparts. The intended area of use is oxidation and dismutation reactions. Control for the syntheses was exerted by protecting either the N-terminal or the C-terminal of the covalently grafted L-histidine molecules. However, since the resin was reported to be amino group selective, covalent grafting was performed with the unprotected amino acid as well. During the preparative work generally applied methods of synthetic organic chemistry (alkylation or esterification) were used. The whole procedure was performed in isopropanol to allow appropriate swelling of the host polymer. After deprotecting the immobilised amino acids the complexes were prepared and the emerging structures (just as the full synthetic procedure) were studied by Photoacoustic Infrared Spectroscopy. The photoacoustic spectra revealed that the grafting was successful in each case and the complexes were formed too. However, real control over the preparation could only be proven when the protected amino acids were applied. On the basis of the spectra and chemical reasoning structural features of the immobilised complexes could be described.

Original languageEnglish
Title of host publicationForum Acusticum Budapest 2005: 4th European Congress on Acustics
Pages1459-1463
Number of pages5
Publication statusPublished - 2005
Event4th European Congress on Acustics, Forum Acusticum 2005 - Budapest, Hungary
Duration: aug. 29 2005szept. 2 2005

Other

Other4th European Congress on Acustics, Forum Acusticum 2005
CountryHungary
CityBudapest
Period8/29/059/2/05

Fingerprint

photoacoustic spectroscopy
histidine
resins
amino acids
polystyrene
infrared spectroscopy
enzymes
organic chemistry
alkylation
polymers
musculoskeletal system
swelling
emerging
catalysts
copper
preparation
oxidation
synthesis
molecules

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Berkesi, O., Szabó, T., Korbély, B., Hernádi, K., & Pálinkó, I. (2005). Covalent grafting of Cu(II)-histidine complexes on polystyrene resin studied by Photoacoustic Infrared Spectroscopy. In Forum Acusticum Budapest 2005: 4th European Congress on Acustics (pp. 1459-1463)

Covalent grafting of Cu(II)-histidine complexes on polystyrene resin studied by Photoacoustic Infrared Spectroscopy. / Berkesi, O.; Szabó, Tímea; Korbély, Barbara; Hernádi, K.; Pálinkó, I.

Forum Acusticum Budapest 2005: 4th European Congress on Acustics. 2005. p. 1459-1463.

Research output: Conference contribution

Berkesi, O, Szabó, T, Korbély, B, Hernádi, K & Pálinkó, I 2005, Covalent grafting of Cu(II)-histidine complexes on polystyrene resin studied by Photoacoustic Infrared Spectroscopy. in Forum Acusticum Budapest 2005: 4th European Congress on Acustics. pp. 1459-1463, 4th European Congress on Acustics, Forum Acusticum 2005, Budapest, Hungary, 8/29/05.
Berkesi O, Szabó T, Korbély B, Hernádi K, Pálinkó I. Covalent grafting of Cu(II)-histidine complexes on polystyrene resin studied by Photoacoustic Infrared Spectroscopy. In Forum Acusticum Budapest 2005: 4th European Congress on Acustics. 2005. p. 1459-1463
Berkesi, O. ; Szabó, Tímea ; Korbély, Barbara ; Hernádi, K. ; Pálinkó, I. / Covalent grafting of Cu(II)-histidine complexes on polystyrene resin studied by Photoacoustic Infrared Spectroscopy. Forum Acusticum Budapest 2005: 4th European Congress on Acustics. 2005. pp. 1459-1463
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