Corticosteroidogenesis by isolated human adrenal cells: Effect of serotonin and serotonin antagonists

K. Rácz, I. Wolf, R. Kiss, Gy Lada, S. Vida, E. Gláz

Research output: Article

15 Citations (Scopus)

Abstract

The direct effect of serotonin and antiserotonin agents on adrenal steroid biosynthesis was studied in isolated adrenal cells derived from patients with Cushing's syndrome. The results indicate that serotonin increases corticosterone production, while the serotonin antagonists cyproheptadine and methysergide depress adrenal steroid-particularly cortisol and aldosterone-biosynthesis.

Original languageEnglish
Pages (from-to)1532-1534
Number of pages3
JournalExperientia
Volume35
Issue number11
DOIs
Publication statusPublished - nov. 1 1979

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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