Coronary flow reserve (CFR), a parameter characterizing the vasodilatory reserve of coronary microcirculation, can be affected by several factors. Left ventricular hypertrophy as an, extravascular compressive force is often associated with abnormalities in coronary microcirculation in patients with aortic stenosis (AOS). In AOS patients with normal epicardial coronary arteries, the CFR is decreased independently the presence or absence of anginal pain. Improvement of CFR can be observed in aortic stenosis patients after aortic valve replacement in parallel with the regression of left ventricular hypertrophy. There is no further decrease in CFR in patients with aortic stenosis with coronary artery disease. Not only CFR but also aortic distensibility is diminished in AOS. In this manuscript the available information regarding this phenomenon in aortic stenosis is reviewed.
|Number of pages||5|
|Journal||Polski Przeglad Kardiologiczny|
|Publication status||Published - nov. 8 2004|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine