Contribution of clinical trials to gross domestic product in Hungary

Zoltán Kaló, János Antal, Miklós Pénzes, Csilla Pozsgay, Zsuzsanna Szepezdi, László Nagyjánosi

Research output: Article

3 Citations (Scopus)


Aim: To determine the contribution of clinical trials to the gross domestic product (GDP) in Hungary. Methods: An anonymous survey of pharmaceutical companies and clinical research organizations (CROs) was conducted to estimate their clinical trial-related employment and revenues. Clinical trial documents at the National Institute of Pharmacy (NIP) were analyzed to estimate trial-related revenues at health care institutions and the value of investigational medical products (IMPs) based on avoided drug costs. Financial benefits were calculated as 2010 US $ purchasing power parity (PPP) values. Results: Clinical trials increased the revenue of Hungarian health care providers by US $165.6 million. The value of IMPs was US $67.0 million. Clinical trial operation and management activities generated 900 jobs and US $166.9 million in revenue among CROs and pharmaceutical companies. Conclusions: The contribution of clinical trials to the Hungarian GDP in 2010 amounted to 0.2%. Participation in international clinical trials may result in health, financial, and intangible benefits that contribute to the sustainability of health care systems, especially in countries with severe resource constraints. Although a conservative approach was employed to estimate the economic benefits of clinical trials, further research is necessary to improve the generalizability of our findings.

Original languageEnglish
Pages (from-to)446-451
Number of pages6
JournalCroatian Medical Journal
Issue number5
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Contribution of clinical trials to gross domestic product in Hungary'. Together they form a unique fingerprint.

  • Cite this

    Kaló, Z., Antal, J., Pénzes, M., Pozsgay, C., Szepezdi, Z., & Nagyjánosi, L. (2014). Contribution of clinical trials to gross domestic product in Hungary. Croatian Medical Journal, 55(5), 446-451.