Continuous epidural or intercostal analgesia following thoracotomy: A prospective randomized double-blind clinical trial

Gábor Debreceni, Z. Molnár, L. Szélig, T. F. Molnár

Research output: Article

44 Citations (Scopus)

Abstract

Background: Pain following thoracotomy is frequently associated with clinically important abnormalities of pulmonary function. The aim of the current study was to compare the efficacy of continuous thoracic epidural analgesia (EDA) to continuous intercostal (IC) block for postoperative pain and pulmonary function in a prospective, randomized, double-blinded clinical trial. Methods: Fifty patients undergoing lung lobectomy for malignancies were randomized into two groups (25/group). Respiratory function (forced vital capacity, forced expiratory volume per 1 s/forced vital capacity, maximum midexpiratory flow rate, peak expiratory flow rate) were evaluated preoperatively, within 4 h after the operation and on the first postoperative day. Visual analog scale (VAS: 0-10) scores were evaluated four-hourly for 20 h. Results: The VAS scores were significantly lower in the EDA versus IC group at the 4th, 8th, and 12th h of observation (mean±SD) 5.5±2.9 vs. 7.3±2.2 P=0.04; 4.1±2.1 vs. 5.1±2.9 P=0.02; 3.6±1.9 vs. 5.2±2.4 P=0.01, respectively. Respiratory function parameters deteriorated significantly in both groups (P

Original languageEnglish
Pages (from-to)1091-1095
Number of pages5
JournalActa Anaesthesiologica Scandinavica
Volume47
Issue number9
DOIs
Publication statusPublished - okt. 2003

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Thoracotomy
Analgesia
Epidural Analgesia
Vital Capacity
Clinical Trials
Lung
Peak Expiratory Flow Rate
Forced Expiratory Volume
Postoperative Pain
Visual Analog Scale
Thorax
Observation
Pain
Neoplasms

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Continuous epidural or intercostal analgesia following thoracotomy : A prospective randomized double-blind clinical trial. / Debreceni, Gábor; Molnár, Z.; Szélig, L.; Molnár, T. F.

In: Acta Anaesthesiologica Scandinavica, Vol. 47, No. 9, 10.2003, p. 1091-1095.

Research output: Article

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