Comparison of the effects of cholestyramine and aluminium hydroxide on the biliary bile acid excretion in rats. An experimental model for the depletion of bile acids in bile

Z. Gregus, A. Barth, E. Fischer, J. Zaumseil, W. Klinger, F. Varga

Research output: Article

8 Citations (Scopus)


Bile flow and biliary excretion of dihydroxy- and trihydroxy-bile acids have been determined in control, cholestyramine (250-2000 mg/kg p.os) and aluminum hydroxide (250-2000 mg/kg p.os) pretreated rats. Cholestyramine proved to be a more potent bile acid depleting agent than aluminium hydroxide. The depressing effect of cholestyramine on bile flow also more significant than that of aluminum hydroxide. Cholestyramine pretreatment seemed to be a suitable experimental model for the depletion of bile acids in rat bile.

Original languageEnglish
Pages (from-to)705-709
Number of pages5
JournalActa biologica et medica Germanica
Issue number6
Publication statusPublished - dec. 1 1980


ASJC Scopus subject areas

  • Medicine(all)

Cite this