Bile flow and biliary excretion of dihydroxy- and trihydroxy-bile acids have been determined in control, cholestyramine (250-2000 mg/kg p.os) and aluminum hydroxide (250-2000 mg/kg p.os) pretreated rats. Cholestyramine proved to be a more potent bile acid depleting agent than aluminium hydroxide. The depressing effect of cholestyramine on bile flow also more significant than that of aluminum hydroxide. Cholestyramine pretreatment seemed to be a suitable experimental model for the depletion of bile acids in rat bile.
|Number of pages||5|
|Journal||Acta biologica et medica Germanica|
|Publication status||Published - dec. 1 1980|
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