The asymmetric induction of (-)-dihydroapovincarninic acid ethyl ester [(-)-DHVIN] and cinchonidine employed as chiral modifiers was compared in the Pd catalysed hydrogenation of the C=C double bonds of phenylcinnamic acid and isophorone. The differences in their effect and behaviour were attributed to the difference in the interaction between the modifier and the reactant and to their different basicity.
ASJC Scopus subject areas
- Process Chemistry and Technology
- Physical and Theoretical Chemistry