A májátültetés szövodményeit és túlélési eredményeit befolyá soló tényezok Magyarországon

B. Nemes, L. Kóbori, Zsuzsa Gálffy, G. Lengyel, Attila Doros, E. Sárváry, F. Perner, Z. Schaff, János Fazakas, F. Szalay, J. Fehér, J. Járay

Research output: Article

7 Citations (Scopus)

Abstract

Demography, morbidity, perioperative characteristics and mortality. Introduction: The authors summarize the demographic, morbidity and mortality characteristics of the Hungarian Liver Transplant Program. They evaluate the changes and development, that has taken place with regard to indications, recipient population and characteristics, operation technique, and peroperative patient management. Method: In order to present the development, data are compared between two time periods (before and after 1999). Categorical variables are evaluated by chisquare test, continuous ones are with Levene Test (for homogeneicity of means), Student T test and Mann-Whitney U-test. Cumulative survivals are computed with Kaplan-Meyer log rank analysis. Variables showed statistical significance on survival bz univariate analysis were then put into multivariate Cox-regression analysis. ROC analysis was performed to set the cut off point of certain continuous parameters in relation to survival. Results: The results are summarized on Tables and statistical Figures. Regarding patients mortality in the beginning the main factors with impact were respectively technical ones like arterial thrombosis, while in the last 4 years perioperative fluid management and transfusion policy became important. Both sepsis and posztoperative renal insufficiency remained key factors for mortality, however their incidence diminished dramatically. Discussion: The overall outcome of the retrospective analysis is, that the program has been developed to European standards with respect to its volume, technical capabilities and results.

Original languageHungarian
Pages (from-to)1567-1574
Number of pages8
JournalOrvosi Hetilap
Volume146
Issue number30
Publication statusPublished - 2005

Fingerprint

Liver Transplantation
Mortality
Survival
Demography
Morbidity
Population Characteristics
Nonparametric Statistics
ROC Curve
Renal Insufficiency
Sepsis
Thrombosis
Regression Analysis
Students
Transplants
Liver
Incidence

Keywords

  • Hungarian
  • Liver transplantation
  • Mortality
  • Outcome
  • Sepsis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{5550756d5ee14197a0e54f02795a13bb,
title = "A m{\'a}j{\'a}t{\"u}ltet{\'e}s sz{\"o}vodm{\'e}nyeit {\'e}s t{\'u}l{\'e}l{\'e}si eredm{\'e}nyeit befoly{\'a} sol{\'o} t{\'e}nyezok Magyarorsz{\'a}gon",
abstract = "Demography, morbidity, perioperative characteristics and mortality. Introduction: The authors summarize the demographic, morbidity and mortality characteristics of the Hungarian Liver Transplant Program. They evaluate the changes and development, that has taken place with regard to indications, recipient population and characteristics, operation technique, and peroperative patient management. Method: In order to present the development, data are compared between two time periods (before and after 1999). Categorical variables are evaluated by chisquare test, continuous ones are with Levene Test (for homogeneicity of means), Student T test and Mann-Whitney U-test. Cumulative survivals are computed with Kaplan-Meyer log rank analysis. Variables showed statistical significance on survival bz univariate analysis were then put into multivariate Cox-regression analysis. ROC analysis was performed to set the cut off point of certain continuous parameters in relation to survival. Results: The results are summarized on Tables and statistical Figures. Regarding patients mortality in the beginning the main factors with impact were respectively technical ones like arterial thrombosis, while in the last 4 years perioperative fluid management and transfusion policy became important. Both sepsis and posztoperative renal insufficiency remained key factors for mortality, however their incidence diminished dramatically. Discussion: The overall outcome of the retrospective analysis is, that the program has been developed to European standards with respect to its volume, technical capabilities and results.",
keywords = "Hungarian, Liver transplantation, Mortality, Outcome, Sepsis",
author = "B. Nemes and L. K{\'o}bori and Zsuzsa G{\'a}lffy and G. Lengyel and Attila Doros and E. S{\'a}rv{\'a}ry and F. Perner and Z. Schaff and J{\'a}nos Fazakas and F. Szalay and J. Feh{\'e}r and J. J{\'a}ray",
year = "2005",
language = "Hungarian",
volume = "146",
pages = "1567--1574",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "30",

}

TY - JOUR

T1 - A májátültetés szövodményeit és túlélési eredményeit befolyá soló tényezok Magyarországon

AU - Nemes, B.

AU - Kóbori, L.

AU - Gálffy, Zsuzsa

AU - Lengyel, G.

AU - Doros, Attila

AU - Sárváry, E.

AU - Perner, F.

AU - Schaff, Z.

AU - Fazakas, János

AU - Szalay, F.

AU - Fehér, J.

AU - Járay, J.

PY - 2005

Y1 - 2005

N2 - Demography, morbidity, perioperative characteristics and mortality. Introduction: The authors summarize the demographic, morbidity and mortality characteristics of the Hungarian Liver Transplant Program. They evaluate the changes and development, that has taken place with regard to indications, recipient population and characteristics, operation technique, and peroperative patient management. Method: In order to present the development, data are compared between two time periods (before and after 1999). Categorical variables are evaluated by chisquare test, continuous ones are with Levene Test (for homogeneicity of means), Student T test and Mann-Whitney U-test. Cumulative survivals are computed with Kaplan-Meyer log rank analysis. Variables showed statistical significance on survival bz univariate analysis were then put into multivariate Cox-regression analysis. ROC analysis was performed to set the cut off point of certain continuous parameters in relation to survival. Results: The results are summarized on Tables and statistical Figures. Regarding patients mortality in the beginning the main factors with impact were respectively technical ones like arterial thrombosis, while in the last 4 years perioperative fluid management and transfusion policy became important. Both sepsis and posztoperative renal insufficiency remained key factors for mortality, however their incidence diminished dramatically. Discussion: The overall outcome of the retrospective analysis is, that the program has been developed to European standards with respect to its volume, technical capabilities and results.

AB - Demography, morbidity, perioperative characteristics and mortality. Introduction: The authors summarize the demographic, morbidity and mortality characteristics of the Hungarian Liver Transplant Program. They evaluate the changes and development, that has taken place with regard to indications, recipient population and characteristics, operation technique, and peroperative patient management. Method: In order to present the development, data are compared between two time periods (before and after 1999). Categorical variables are evaluated by chisquare test, continuous ones are with Levene Test (for homogeneicity of means), Student T test and Mann-Whitney U-test. Cumulative survivals are computed with Kaplan-Meyer log rank analysis. Variables showed statistical significance on survival bz univariate analysis were then put into multivariate Cox-regression analysis. ROC analysis was performed to set the cut off point of certain continuous parameters in relation to survival. Results: The results are summarized on Tables and statistical Figures. Regarding patients mortality in the beginning the main factors with impact were respectively technical ones like arterial thrombosis, while in the last 4 years perioperative fluid management and transfusion policy became important. Both sepsis and posztoperative renal insufficiency remained key factors for mortality, however their incidence diminished dramatically. Discussion: The overall outcome of the retrospective analysis is, that the program has been developed to European standards with respect to its volume, technical capabilities and results.

KW - Hungarian

KW - Liver transplantation

KW - Mortality

KW - Outcome

KW - Sepsis

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AN - SCOPUS:25444531496

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